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Category: Volume 06 Issue 11 November 2018
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Title: Amniotic Membrane transplantation for corneal surface reconstruction

Authors: Suchismita Mishra, Jayashree Dora, Ramesh Chandra Mohapatra, Pragati Jain, Swati Samant

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.08

Abstract

Objectives: To evaluate the efficacy of fresh human amniotic membrane for reconstruction in corneal surface diseases.

Material and Methods: 28 eyes of 26 patients with corneal surface disorders were evaluated.  Indications for AMT included bullous keratopathy (4 eyes), climatic droplet keratopathy (3 eyes), Steven Johnson syndrome (7 eyes), chemical injury(3 eyes), corneal ulcer (7 eyes), band keratopathy (2 eyes) and shield ulcers (2 eyes). Fresh amniotic membrane was used in all the cases.

Result: The age range was from 18-65 years, out of which 15 were males and 11 were females. Success was noted in75% (21/28 eyes) with very few complications in an average follow up period of 6 months. The mean epithelisation time varied from 2 – 2.4 weeks.

Conclusion: Fresh amniotic membrane can reduce inflammation, promote epithelisation and decrease in various corneal surface disorders.

Keywords: AMT, AM, Human amniotic membrane, corneal surface disorder, SJS.

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Corresponding Author

Dr Swati Samant, MS          

Associate Professor, Department of Ophthalmology, IMS and SUM Hospital

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