Details
Category: Volume 06 Issue 07 July 2018
Hits: 1155

Title: Seroprevalence of HIV in Women Attending Antenatal Clinic at Sultania Zanana Hospital, Gandhi Medical College Bhopal

Author: Garima Gupta

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.123

Abstract

Background: Human Immunodeficiency Virus (HIV) infection is increasing at an alarming rate globally. Apart from heterosexual route, mother to-child transmission is the next most important route of HIV transmission accounting for over 90% of infections in children. The present retrospective study is undertaken to evaluate the effectiveness of implementation of PPTCT programme in SZH, GMC Bhopal.
Material and Methods: Pregnant women attending antenatal OPD from 2011 to 2015 were tested for HIV by Rapid Test which included pre and post-test counselling. Antiretroviral prophylaxis with nevirapine was given to seropositive mother-baby pairs during delivery.
Results: A total of 78582 ante-natal women were counselled and 99.98% (78574) of them gave consent for HIV testing. Seropositivity in these women was 0.08% (67 cases). The no. of positive deliveries (109) exceeded the no. of positive antenatal cases (67). 11 women opted for pregnancy termination, 69.7% were delivered through vaginal route. There were 90.82% (99) live births. 89.9% (89) mothers opted for exclusive breastfeeding. All the newborns received nevirapine prophylaxis.
Conclusion: PMTCT services - counselling and testing should be provided to all ANCs. EDD-based tracking, institutional deliveries, postnatal counselling to be encouraged along with complete MB pair coverage, capacity building of concerned staff regarding delivery of HIV+ve ANCs and exposed children tracking.
Keywords: Antiretroviral therapy, HIV, Nevirapine, Seroprevalence.

References

  1. Hay PE, Sharland M, Ugwumadu AHN. Infections in pregnancy In: Chamberlain G, Steer PJ, editors. Turubutt's   Obstetrics, 3rd edn. London: Churchill Livingstone; 2001.p. 356-81.
  2. gov [Internet]. Atlanta: Fact sheets: HIV among pregnant women, infants and children in the United States; c2012-13 [updated 2013 Feb 12; cited 2013 Mar 3]. Available from: http://www.cdc.gov/hiv/topics/ perinatal/index.htm
  3. National AIDS Control Programme Phase IV: Working groups Reports- ICTC/PPTCT [internet]. Government of India: National Control Organization (NACO) c2007– [cited 2012 Nov 28]. Available from: http://www.nacoonline.org.
  4. Boerma JT et al. Estimates of HIV-1 prevalence from national population-based surveys as a new gold standard. Lancet 2003; 362: 1929-31. http://dx.doi.org/10.1016/S0140-6736 (03)14967-7
  5. Laboratory diagnosis, biosafety and Quality control [internet]. Government of India: National AIDS Control Organization (NACO). c2007 – [cited 2012 May 29].Available from: http://www.nacoonline.org.
  6. Swarn Gupta, Dinesh Kumar. “A Retrospective Five Years Study of PPTCT Programme in SMGS Hospital,  ” Journal of Evolution of Medical and Dental  Sciences 2015; Vol. 4, Issue 100, December 14; Page:  16554-16557, DOI: 10.14260/jemds/2015/2464
  7. Vellanki VS, et al Seroprevalance of HIV in women attending antenatal clinic at KIMS hospital, Narketpall Int J Reprod Contracept Obstet Gynecol. 2012 Dec;1(1):17-21.
  8. Kulkarni SK, Doibale MK. Trend of seroprevalence of HIV among antenatal clinic attendees at a tertiary care hospital international journal of basic and applied medical sciences 2013) January-April ;3(1):257-262.
  9. Giri PA, Bangal VB, Phalke DB. Prevalence of HIV among rural pregnant women attending antenatal clinics at Pravara Rural Hospital, Loni, Maharashtra, India. Int J Health Allied Sci 2012;1:13-5.
  10. Glynn JR, Carael M, Buve A, Anagonou S, Zekeng L, Kahindo M, et al. Does increased general schooling protect against HIV infection? A study in four African cities. Trop Med Int Health 2004;9:4-14. http://dx.doi.org/10.1046/j.1365-3156.2003.01168.x
  11. Chirwa WC. Migrant labour, sexual networking and multi-partnered sex in Malawi. Health TransitionReview 1997;7:5-15.
  12. Ghani AC, Swinton J, Garnett GP. The role of sexual partnership networks in the epidemiology of gonorrhea. Sex Transm Dis 1997;24:45–56. http://dx.doi.org/10.1097/00007435-199701000-00009.
  13. Bal R, Talukdar A, Roy K. Prevention of parent to child transmission of HIV -scenario of West Bengal. J Obstet Gynecol India 2008;58:221-5.
  14. Prevention of Mother to Child transmission of HIV (MTCT). Available at www.avert.org/motherchild.htm. Accessed 14 October 2012.
  15. Saini VK, Sharma SV. Recent trends of HIV transmission from mother to child: Retrospective study of 4 years in a tertiary centre. International Journal of Scientific Research. Volume 4, Issue 9 Sept 2015.
  16. Kourtis AP, Jamieson DJ, de Vincenzi I, Taylor A, Thigpen MC, Dao H, et al. Prevention of human immunodeficiency virus -1 transmission to the infant through breastfeeding: new developments. Am J Obstet Gynecol 2007 sep;197(3 suppl);S113-22.
  17. World Health Organization: HIV transmission through breast feeding; A review of available evidence: 2007 update. Geneva, WHO Press, 2008.

Corresponding Author

Dr Garima Gupta

Department of Obstetrics and Gynecology, Sultania Zanana Hospital, Gandhi Medical College, Bhopal, Madhya Pradesh, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone: 07049090775