Title: Medical Treatment of Distal Ureteric Stone
Authors: Dr Rajeev Kumar Singh, Dr Prateek Shakya
DOI: https://dx.doi.org/10.18535/jmscr/v6i7.106
Abstract
Various treatment modalities are available in the market for the treatment of distal ureteric stone. This study was conducted to evaluate the efficacy of tamsulosin as an expulsive pharmacologic therapy for the treatment of distal ureteral stone.100 patients over 15 years of age who were diagnosed as a case of distal ureteric calculi of size less than or equal to 8mm were included in the study and they were randomized blindly into two groups with 50 patients in each group . Group A Patients were given Cap Tamsulosin 0.4 mg, 1 daily up to 4 weeks while group B patients were given placebo, 1 Cap daily up to 4 weeks. Both groups were given tab diclofenac Sodium 50 mg, 1 tab 8 hourly for pain control on required basis and advice to drink plenty of water. Patients were evaluated with plain X-Ray KUB and USG whole abdomen after one week, two week, three week and four weeks. The primary endpoint was expulsion rate. Expulsion time, need for analgesics, need for hospitalization and drug side effects were secondary endpoints. Both group contains 50 patients .Mean age of patients in Group A is 31.90±5.76 and in Group B is 33.14±5.97.Mean stone size was 6.87mm in greatest dimension. Regarding age, sex, stone size and stone lateralization (right/left), there was no significant difference between the group A and B. A stone expulsion rate of 78% (39 patients) was noted in group A and 48% (24 patients) in group B. Group A revealed a statistically significant advantage in term of stone expulsion rate (p=0.0018).By using tamsulosin a higher stone expulsion rates can be achieved in a shorter time.
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