Title: The effect of Pterygopalatine Canal Injection with Local Anaesthetic and Adrenaline on Bleeding during Functional Endoscopic Sinus Surgery

Authors: Rohit Bhardwaj, MS, Gul Motwani, MS, Rajeev Kumar Verma, Ms Namrata Yadav, Sandeep Trehan

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i5.95

Abstract

Introduction: Control of bleeding is important for a safe and effective procedure, as it improves visualization of intranasal anatomy & decreases the risk of complications. Mucosal bleeding is increased in presence of inflammation as seen in chronic rhino-sinusitis during FESS.  This study was doneto assess the effect of pterygopalatine canal injection with xylocaine and adrenaline on intraoperative surgical field bleeding, surgery duration & overall blood loss during FESS in comparison to opposite side.

Methods: Prospective single blind randomized controlled trial was performed including 30 patients in a tertiary care Centre. Symmetrical chronic rhinosinusitis (based on Lund-Mackay CT Scoring) patients, undergoing FESS were included. Each served his/her own control since injection containing 2 mL of xylocaine with 1:100000 adrenaline was injected in pterygopalatine canal on one side only. Injection side was decided by lottery method for which operating surgeon was kept blind. Surgical field bleeding graded every 15 minutes based on 6point scale used by Boezaart et al. Surgery was completed on one side first. Total blood loss, surgery duration was computed separately for both sides.

Results: 29 out of 30 patients showed beneficial results of pterygopalatine block in terms of improvement in intra operative surgical field bleeding, reducing surgery time & overall blood loss. Average bleeding grade at 45 and 60 minutes on control arm represented by median (interquartile range) 3 (3-3) & 3 (2-3) respectively and on intervention arm 2 (2-2) & 2 (2-2) having P value of < 0.0001for both is statistically significant. Surgery time in intervention arm showed significant improvement in comparison with control side having p value of 0.007. Improvement was noted in overall blood loss favoring intervention arm (p value <.0001).

Conclusion: Injection of the pterygopalatine canal resulted in improvement in surgical field bleeding, shortened surgery time and reduced overall blood loss in intervention arm.

Keywords: Pterygopalatine Canal, Bleeding, FESS, Adrenaline, Local Anaesthetic, Rhinosinusitis, Surgery Duration.

References

  1. Stankiewicz JA. Complications of endoscopic sinus surgery. Otolaryngol Clin North Am 1989;22:749–58
  2. Saitoh K, et al. Induced hypotension for endoscopic sinus surgery. Masui 51:1100–1103, 2002
  3. Riegle EV, Gunter JB, Lusk RP, et al. Comparison of vasoconstrictors for functional endoscopic sinus surgery in children. Laryngoscope 102:820–823, 1992.
  4. Hatho’n IF, Habib AR, Manji J, Javer AR. Comparing the reverse Trendelenburg and horizontal position for endoscopic sinus surgery: a randomized controlledtrial. Otolaryngol Head Neck Surg2013; 148:308-13
  5. Nair S, Collins M, Hung P, Rees G, Close D, Wormold PJ. The effect of beta-blocker premedication on the surgical field during endoscopic sinus surgery. Laryngoscope. 2004 Jun;114(6):1042-6
  6. Eberhart LH, Folz BJ, Wulf H, Geldner G. Intravenous anaesthesia provides optimal surgical conditions during microscopic and endoscopicsinus surgery. 2003 Aug;113(8):1369-73
  7. Lund VJ, Kennedy DW. Staging for rhino sinusitis.Otolaryngol Head Neck Surg1997Sep;117(3 Pt 2):S35-40.
  8. Mercuri LG. Intraoral second division nerve block. Oral Surg Oral Med Oral Pathol 1979;47:109–13
  9. Douglas R, Wormald PJ. Pterygopalatine fossa infiltration through the greater palatine foramen: where to bend the needle. Laryngoscope 2006;116:1255–7
  10. Peter John Wormald. Endoscopic sinus surgery. 3. New York: Thieme Medical Publishers; 2012
  11. Schubert MS. Allergic fungal sinusitis: Pathogenesis and management strategies. Drugs 64:363–374, 2002.
  12. Lepere AJ. Maxillary nerve block via the greater palatine canal: new look at an old technique. Anesth Pain Control Dent 1993;2: 195–7
  13. Wormold PJ, Athanasiadis T, Rees G, Robinson S. An evaluation of pterygopalatine fossa injection with local anaesthetic and adrenaline in the control of nasal bleeding during endoscopic sinus surgery.AmJRhinol 2005 May-Jun;19(3):288-92
  14. Bharadwaj VK, Novotny GM. Greater palatine canal injection: an alternative to the posterior nasal packing and arterial ligation in epistaxis. J Otolaryngol 1986;15:94–100
  15. Gurr P, Callanan V, Baldwin D. Laser-Doppler blood flowmetry measurement of nasal mucosa blood flow after injection of the greater palatine canal. J Laryngol Otol1996;110:124–8
  16. CJ Valdes, Y AL Badaii, M Bogado, M Samaha. Does pterygopalatine canal injection with local anaesthetic and adrenaline decrease bleeding during functional endoscopic sinus surgery?  J LaryngolOtol 2014 Sep;128(9):814-7.

Corresponding Author

Dr Rajeev Kumar Verma

Krashi Upaz Mandi Roadm Srimadhopur

Distt. Siker (Rajasthan) India

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