Title: Aetiologcal and Clinical Profile of Hematuria in Children between 1 month to 12 Years
Authors: Shermin Nasreen.A, Karthika Gopan.P
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.40
Abstract
Objective: To evaluate the clinical and etiological profile of hemauria in children and to describe the course of illness till the end of one year
Methodology: Prospective follow up study of a case series in a tertiary care teaching hospital in Kerala, South India during the period January2001-2002. Data collection and evaluation were done during initial workup and follow up assessment and relevant investigation were done during subsequent visits.
Results: The study population included 100 children admitted with hematuria during the period of study. Hematuria was found to be a major problem of school going children of age 6-12 years (57%) with slight female preponderance (52%). Highest incidence was occurred in August and December. Majority belong to low socioeconomic status (42%) and were residing around Thiruvananthapuram district. At the time of admission 60% diagnosed as PIGN,22% as microscopic hematuria of which UTI-9%,infective endocarditis -1%, Ideopathic (12%) (7 had persistent hematuria on follow up). remaining 18% were contributed by septicemia, snakebite, HSP, HUS, Abdominal mass etc.75 of them followed up for one year. During follow up among the non biopsied (40) cases, Post infectious glomerulonephritis (PIGN) (59%), sepsis-5(12%),UTI-5(12%), Snake bite-3(7%),nephrolithiasis-2(5%),Ideopathic-2(5%) were there. Renal Biopsy was done for 35 cases (46.6%). Among the biopsied cases IGA nephropathy-8(23%)(all between 9-12 years), SLE-6(17%), PIGN-4(11.4%), DPGN-4(11.4%), HUS-3(8.5%), HSP-3(8.5%), FSGS-3(8.5%), Thin basement membrane disease-2 (5.7%), ATN-2(5.7%)
Conclusion: Among the 3.8% total admissions of hematuria PIGN was the leading cause(59% non biopsied cases and 11.4% biopsied cases)followed by IGA Nephropathy(23%) and SLE (17%). 60% of hematuria resolved by one year & there were no deaths due to hematuria till the end of 12 month follo.
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