Title: An Unusual Case of Chlorpyrifos Intoxication-Organophosphorus Poisoning: A Case Report
Authors: Sara Sana Ayesha Khanum, Dr Shaheda Siddiqui, Salva Fatima Heba, Safura Sultana, Rahmat Fida
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.54
Abstract
Intentional poisoning with organophosphorus compounds continues to be a leading cause of hospital admission. These kinds of cases are generally reported in under-resourced countries like India, where women are mainly engaged in agricultural work for their livelihood. With the prevalence of such cases becoming common, their severity can be accessed through scientific methods and other clinical databases. So that a uniform and effective management can be done according to standard guidelines. This case report mainly says about the treatment strategies and management of deliberate intoxication of chlorpyrifos compound by women which are known to produce damaging effects on the human nervous system. The patient was observed with clinical symptoms of excessive salivation, lack of movement and pinpoint pupil. On administration of antidote therapy i.e. 1 ampoule of Atropine Sulphate (1.2mg) and 1gm Pralidoxime intravenous (IV) bolus as a loading dose, decreases the rate of morbidity and mortality. The given antidote was according to the World Health Organization criteria. Other strategies like patient counseling, psychosocial and educational programs can be very effective and should be recommended.
Keywords: organophosphorus poisoning, deliberate self-harm, chlorpyrifos, pralidoxime, atropine sulfate.
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