Title: Association of Level of HbA1c with Severity of Diabetic Retinopathy
Authors: Sadhana Sewak, Yadvendra Singh Solanki, Chandrasheela Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.22
Abstract
Introduction: Diabetes is a major Global health epidemic. WHO predicted India to be Diabetic capital of the world. Diabetic Retinopathy arises as chronic microvascular complications of diabetes. Various factors regulate the progression of the disease. The prime systemic risk factor is hyperglycemia. This study was aimed to assess the association of HbA1c level with severity of retinopathy.
Methodology: Randomly selected type 2 diabetic patients at Goma Bai Netralaya of Neemuch, M.P., were examined for retinopathy by retina specialists and HbA1c was determined clinically. Analysis of variance test was used to determine the relationship between HbA1c and severity of retinopathy
Results: Prevalence of retinopathy was found higher in NPDR (43.75%) group than PDR (37.54%). Normal range of was kept as<7 %. HbA1c values showed significant difference between NPDR and PDR than controls. Analysis of variance for HbA1c with different groups of retinopathy is highly significant (p<0.01).
Conclusion: The value of glycosylated haemoglobin showed an increasing trend with increase of severity of diabetic retinopathy. Good glycemic control of diabetes with target HbA1c of 7.0% and regular Ophthalmic screening for diabetic retinopathy changes will reduce morbidity due to diabetic retinopathy.
Keywords: Microvascular, Diabetic Retinopathy, Hyperglycemia, Glycosylated haemoglobin,
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