Title: Characterization, Estimation and Evaluation of Antifungal Activity of Lipids Isolated from Iraqi Capparis spinosa Leaves Buds

Authors: Abbas Dawwas Matter Al-Maliki, Majda Ismaeel Abd- Al-Majeed, Makarem Abdul Razzak Jassem Al-Abdal, Ban Abdul- Majeed Esmaeel

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i11.01

Abstract

The current work was carried out to isolate , characterize , estimate and evaluate the biochemical activity of lipids from Iraqi Capparis spinosa L. leaves buds against three pathogenic fungi. The active isolated lipids were identified by using Gas chromatography- mass spectroscopy (GC-MS) technique. The concentration of 0.10, 0.15, 0.20, 0.25 and 0.30 mg/ml recorded inhibition zone diameters equal to 10,17,16,17 and 17   mm respectively against Aspergillus flavus fungus. Also the same concentrations showed inhibition zone diameters represented by 17,16,19,19 and 19 mm respectively against Rhizopus fungus whereas the concentrations of active lipids gave 40,37,35,25 and 25 mm respectively towards growth of Candida albicans fungus. Therefore the isolated active lipids of Capparis spinosa leaves buds can be used safely to treat various diseases caused by these pathogenic micro-organisms instead of antibiotics but this work demands further clinical and pharmaceutical studies.

Key words: Capparis spinosa, Active lipids, Pathogenic fungi, GC-MS technique, Active chemical groups

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Corresponding Author

Majda Ismaeel Abd- Al-Majeed*

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