Title: Evaluation of Serum Markers in Cirrhosis of Liver and Alcoholic Liver Disease
Authors: Dr M. Madan Mohan Rao, Dr G.Anitha, Salma Mahaboob R, G. Obulesu
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.197
Abstract
Liver disease is a general term for any damage that reduces the functioning of the liver. As a large organ, the liver shares with many other organs the ability to perform its functions with extensive reserve capacity.
Aim: aim of the study was study of serum markers in cirrhosis of liver and alcoholic liver disease.
Materials and Methods: The present study was done in the department of General Medicine at Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India. The present study was carried out on total 150 subjects aged between 35-60 years. Subjects were divided into three groups. 50 subjects were cirrhosis of liver and 50 were alcoholic liver disease. Control group which consist of 50 subjects who had no complain and history of liver disease.
Results and Discussion: The various enzymatic parameters included in LFT’S are Serum Bilirubin, SGOT, SGPT, GGT & ALP. These are useful to diagnose various liver diseases from the present study it is observed that in alcoholic Liver Disease shows a highest rise in Gama glutamyl transferase, high levels of GGT lives are the markers in the diagnosis of alcoholic liver disease. In cirrhosis of liver SGOT and SGPT levels are high these shows that these are the marker enzyme for cirrhosis of liver.
Conclusion: Further study is require for the diagnosis of markers in liver disease
Keywords: Cirrhosis of liver, Alcoholic liver disease, SGOT,SGP,ALP.
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