Title: Single Puncture CT Guided fine-needle aspiration cytology (FNAC) and Tru-cut biopsy in Indeterminate Lung Lesions
Authors: Dr Richa Verma, Dr Shikha Sood, Dr Sanjiv Sharma, Dr Navneet Sharma, Dr Sudarshan Kumar Sharma, Dr Malay Sarkar
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.83
Abstract
Purpose
1. To establish cytological and histopathological diagnosis of indeterminate focal and diffuse lung lesions
2. Comparison of coaxial lung FNAC and trucut biopsy
3. Combined complications of coaxial lung FNAC and trucut biopsy
4. Establishment of guidelines to use FNAC or Tru-cut biopsy or both in different indeterminate lung lesions
Materials and Methods: Single puncture co-axial FNAC and biopsy was done in 76 patients referred to the department of radiodiagnosis, Indira Gandhi Medical College, Shimla who had indeterminate lung lesions on contrast enhanced CT. Role of co-axial biopsy needle in diagnosing indeterminate lesion was explored and comparison of both the techniques along with their complications was done using appropriate statistical tests.
Results: Overall sensitivity of biopsy (81.08%) was higher than FNAC (74.29%) but its specificity was low (50% versus 83.3%). Sensitivity of biopsy for benign lesion was higher than FNAC (83.3% versus 76.6%) but was comparable for malignant lesions (76.92% versus 76.6%). Hence FNAC and biopsy are complem-entary to each other than done alone (sensitivity 94.59%, specificity 97.22%).
Conclusion: Both the CT guided coaxial FNAC and trucut biopsy are complementary and should be done in a single sitting for a better diagnostic yield .Use of coaxial needle is more convenient for the patients rather than single biopsy needle.
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