Title: A Histopathological Review of Nephrectomy Specimens Received in a Tertiary Care Hospital-A Retrospective Study
Authors: Dr Bharti Devi Thaker, Dr Kailash Singh
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.167
Abstract
Introduction: Simple and Radical nephrectomies are done for benign and malignant lesions of kidney respectively. This study was conducted to find out the Histopathological spectrum of diseases that were encounteredin these received nephrectomy specimens and compare it with other studies over a period of 2 years in department of pathology, GMC Jammu retrospectively.
Result: A total of 70 nephrectomy specimens were received. Male constituted 40 cases (57%) and females 30 cases (43%). Age range of cases was from 3 year to 70 year. The highest percentage of patient belonged to age group 41-50 years. Non Neoplastic (62 cases) were most common followed by malignant cases and the least common were benign tumours. Chronic pyelonephritis (30cases) was the most common inflammatory condition for which nephrectomy was done.Among the malignant tumour clear cell renal carcinoma (3 cases) was the most frequent. Most common clinical symptom was flank pain.
Conclusion: Non neoplastic lesions were more common than neoplastic lesion. Chronic pyelonephritis was the most common histopathological diagnosis. Renal cell carcinoma was most common among the malignant tumours.
Keywords: nephrectomy, pyelonephritis, benign ,malignant.
References
1. Aiman A, Singh K, Yasir M. Histopathological spectrum of lesions in nephrectomy specimens-Afive year experience in tertiary care hospital.Jsci Soc 2013;40:148-54.
2. Ozen H, Colowick A, Freiha FS. Incidentally discovered solid renal massess. What are they? Br J Urol 1993;72:274-6.
3. Motzer RJ, Bancer NH, Nanus DM. Renal Cell carcinoma. N Eng J Med 1996;355:865-75.
4. Truong LD, Shen SS, Park MH et al. Diagnosing non neoplastic lesions in nephrectomy specimens. Arch Pathol Lab Med 2009;133:189-200.
5. Lathif F, Mubarak M, Kazi JI. Histopathological characterstics of adult renal tumours:a preliminary report. J Pak Med Assoc 2011;61:224-8.
6. Badmus TA, Salako AA, Sansui AA et al.Adult nephrectomy: our experience at Ile- Ife. Niger J Clin Pract 2008;11(2):121-6.
7. Rafique M. Nephrectomy: Indications, complications and mortality in 154 consecutive patients.J Pak Med Assoc 2007;5:35-8.
8. Shaila, Nityananda B.S , Tamil Arasi. Spectrum of lesions in Nephrectomy Specimens in a Tertiary care Hospital . J Evo Med Den Sci .2015;4(73):12714-12726.
9. Mannan R, Kaur H, Singh PA et al. A Histopathological spectrum of Renal lesions : A 3 year prospective study of a Tertiary care teaching centre. Int J Dent Med Res 2015;1(6): 11-13.
10. Popat VC, Kumar MP, Udani M et al. A study on culprit factors ultimately demanding nephrectomy. Internet J Urol.2010;7.
11. Ghalani IF. Pathological spectrum of Nephrectomies in a general Hospital. Asian J Surg 2002;25:163-9.
12. Amin AN, Pushpalatha Pai, Krishnaraj Upadhyaya. A Histopathological spectrum of Nephrectomy Specimens in a Tertiary care Hospital in southern India. Intl J Bio Med Res .2015;6(3):5173-5178.