Title: A Study on Antibiotic Sensitivity Pattern of Salmonella Typhi in Pediatric Age Group

Authors: Suresh.K., Balachandran C.S., Yogavalli.S, Chidambaranathan.S

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.129

Abstract

 Multidrug resistance in Salmonella Typhi has emerged as a significant problem. Given the difference in the sensitivity patterns reported for Salmonella Typhi, this study aimed to evaluate antimicrobial susceptibility patterns of Salmonella Typhi in RMMCH, Chidambaram, India. Salmonella Typhi positive blood cultures from children up to 12 years of age, over a period of 22 months from November 2014 to August 2016 were analyzed. Kirby-Bauer disc diffusion method was used to evaluate antimicrobial susceptibility.

Results: Of the total of 20 isolates studied, all the isolates were susceptible to ceftriaxone, Cefixime and Azithromycin. most were responsive to Ciprofloxacin, Nalidixic acid and Chloramphenicol. Maximum resistant noted against Ampicillin. In this study 10% of isolates were MDR.

Key words: Antibiotic sensitivity, Salmonella typhi, multidrug resistant typhoid fever, Pediatric age group.

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Corresponding Author

Suresh.K.

Postgraduate, Department of Pediatrics,

Rajah Muthiah Medical College and Hospital,

Annamalai University, Annamalai Nagar – 608 002