Title: Breast Conservation Surgery after Neoadjuvant Chemotherapy in Responders in Operable Breast Carcinoma: A Better Alternative.
Authors: Kunjan Sharma, Dhruv Sharma, S.S MInhas
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.116
Abstract
Background: This was follow up of twenty five female patients of operable breast cancer in a prospective study in a tertiary care centre over a period of one year from 1st September,2006 to 31st August,2007 regarding response to neoadjuvant chemotherapy and conversion of modified radical mastectomy to breast conservation surgery.
Aim: To observe the events during years of follow up and to study whether breast conservation surgery in carefully selected responders could prove to be a better alternative.
Material and Methods: The study was conducted in fine needle aspiration cytology proven operable breast cancer patients with ductal histology. Inclusion criteria were female patients with complete haemogram, liver function tests, renal function tests within normal limits, Karnofsky score more than fifty and age below 70 years. Exclusion criteria were patients with pregnancy or previous history of thoracic irradiation.
Results: 16 of 25 patients were offered breast conservation surgery after neoadjuvant chemotherapy according to selection criteria and kept on follow up after treatment completion. Two patients developed ipsilateral breast recurrence at four and six years of follow up respectively.
Conclusion: Breast conservation surgery seems to be a safe and better alternative in carefully selected responders.
Keywords: Neoadjuvant chemotherapy ,Breast conservation surgery, Modified radical mastectomy
Abbreviation: BCS; Breast conservation surgery, MRM; Modified radical mastectomy, IBTR; Ipsilateral breast tumour recurrence.
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