Title: Outcome of Diabetic Foot Ulcer Management with Vacuum Assisted Closure

Authors: Dr Prince H.P., Dr Sreejayan. M.P Dip.NB., Ph.D., FRCSEd., FRCS (Glasg)

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i3.157

Abstract

Vacuum assisted dressing has been advocated as a novel method in the treatment of diabetic foot ulcer by stimulating the chronic wound environment   Also known as Negative pressure wound therapy (npwt).  A total of 100 cases clinically presenting with diabetic foot ulcer were included in the study. Fifty patients were enrolled in regular dressing group and the other 50 in VAC group. Outcome was measured using wound scoring system, duration of stay in hospital and categorizing outcome. In our clinical study after 8 days of admission 20% of patients who underwent VAC dressing had shown a high wound score compared to only 2% with normal dressing. Hospital stay and number of amputation were less with VAC dressing.  Hence concluded that VAC therapy enhanced granulation tissue formation leading to better wound  healing  and faster recovery. Vac is thus a promising new technology in the field of wound healing.

Keywords - VAC, negative pressure wound therapy, wound healing.

References

1.      Eginton MT brown KR, seabrook GR et al. a prospective randomized evaluation of negative pressure wound dressings for diabetic foot wounds Ann Vasc Surg. 2003 Nov;17(6):645-9.

2.      Banwell PE, Teot L. Topical negative pressure (TNP): the evolution of a novel wound therapy. J Wound Care 2003; 12:22–8

3.      Venturi ML, Attinger CE, Mesbahi AN, et al. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) Device: a review. Am J Clin Dermatol 2005; 6:18

4.      Banwell PE. Topical negative pressure therapy in wound care. J Wound Care 1999; 8:79

5.      Armstrong DG, Lavery LA, Boulton AJ. Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity? Int Wound J 2007;4(1):79–86

6.      M.J. Morykwas, L.C. Argenta, E.I. Shelton-Brown, W. McGuirt Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation Ann Plast Surg, 38 (6) (1997), pp. 553–562

7.      Blume PA, Walters J, Payne W, Ayala J, Lantis J. Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial. Diabetes

8.      Morykwas MJ, Simpson J, Punger K, Argenta A, Kremers L, Argenta J. Vacuum-assisted closure: State of basic research and physiologic foundation. Plast Reconstr Surg 2006;117:121S-6

9.      Mouës CM, Vos MC, van den Bemd GJ, Stijnen T, Hovius SE. Bacterial load in relation to vacuum-assisted closure wound therapy: A prospective randomized trial. Wound Repair Regen 2004;12:11-7

10.  Stinner DJ, Waterman SM, Masini BD, Wenke JC. Silver dressings augment the ability of negative pressure wound therapy to reduce bacteria in a contaminated open fracture model. J Trauma 2011;71:S147-50

11.  Mark TE, Kellie RB, Gary RS, Jonathan BT, Robert AC. Prospective randomized evaluation of negative–pressure wound dressing for diabetic foot wounds. Ann Vasc Surg. 2003;17:645–9. [PubMed]

12.  Prabhdeep SN, Sanjeev KU, Ramneesh G, Kuljyot B, Shirin G. Role of negative pressure wound therapy in healing of diabetic foot ulcers. J Surg Tech Case Rep. 2011;3:17–22. [PMC free article]  [PubMed]

14.  Apelqvist J, Armstrong DG, Lavery LA, Boulton AJ. Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds. Am J Surg. 2008;195:782–8. [PubMed]

Corresponding Author

Dr Sreejayan. M.P Dip.NB., Ph.D., FRCSEd., FRCS (Glasg)

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., 9745636707