Title: Ocular Morbidity of Preterm Infants Screened for Retinopathy of Prematurity at 2 Years of Age – A Prospective Follow up Study

Authors: Dr Anitha S. MS, Dr Resmi P Haridas MS

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i3.102

Abstract

Background: Prematurity by itself carries a lifelong increased risk of ocular morbidity, regardless of whether the baby developed acute phase ROP. When visual acuity and contrast sensitivity are measured later in life for children born prematurely compared to term birth, median values are significantly lower. Prematurity can later lead to sequelae which is mainly divided into 4 categories; visual functions, strabismus, refractive errors mainly myopia and those affecting the ocular structure like retinal detachment, glaucoma, cataract.

Thus we can infer that, ROP as such is not preventable but the blindness from ROP is one of the few causes of childhood visual disability in which blindness should, by timely treatment, be prevented. There is also need for long term follow up of these children to detect any sequelae.

Materials and methods- Prospective consecutive case series of preterm infants screened for ROP at a tertiary eye care center over a period of 2 years.

Results- Refractive errors occurred more frequently in the premature babies as compared to the general population. Among refractive errors, myopia predominated in all groups. The prevalence of refractive errors and the degree of myopia were significantly affected by the presence of ROP, everity of ROP, decreasing birth weight and gestational age. Astigmatism also occurred more frequently in the ROP group. Degree of astigmatism was also higher in the ROP group as copared to the premature babies without ROP.

Among other problems affecting ocular structure, Strabismus had a significant association to the presence of ROP. All other sequelae like cataract, nystagmus, retinal detachment and anterior segment problems were only seen in the cicatricial ROP group.

Conclusions- This study stresses the need for early screening of premature babies for the presence of refractive errors and other problems of ocular structure like strabismus, nystagmus, cataract which can enable these babies to have a normal visual development especially in developing countries where there is a rise in neonatal services.

Key Words – Prematurity, Retinopathy of prematurity, Strabismus, Refractive errors.

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Corresponding Author

Dr Anitha S. MS

Associate Professor, Regional Institute of Ophthalmology

Trivandrum, Kerala INDIA

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