Title: Proliferating Trichilemmal Tumor
Authors: Dr Raghupathi.S, Dr Prakash, Dr Suma.S, Prof.P N Sreeramulu
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.58
Abstract
The proliferating trichilemmal tumor (PTT) is a lesion with trichilemmal differentiation, more common occurring among elderly women; it affects the scalp with sizes ranging from 2to 10 cm. Microscopically, it is solid-cystic, well-defined, affecting the dermis and the subcutaneous cellular tissue. It presents trichilemmal and squamous keratinization. Pleomorphism may be present. Ghosts, apocrine and spindle cells can be observed. The differential diagnosis should be performed with malignant trichilemmal tumor and squamous cell carcinoma. Their behaviour is benign and complete resection is recommended. Herein, we report a case of well differentiated low-grade malignant PTT due to its rarity.
Keywords: Proliferating trichilemmal tumor (PTT), Squamous keratinization
References
1. LeBoit PE, Burg G, Weedon D, Sarasain A, editors. World Health Organization. Classification of tumours. Pathology and genetics of skintumours. IARC Press: Lyon; 2006.
2. Wilson-Jones E. Proliferating epidermoid cysts. Arch Dermatol. 1966;94: 11-9.
3. Mones JM, Ackerman AB. Proliferating trichilemmal cyst is asquamous-cell carcinoma. Dermatopathology, practical & conceptual.1984; 4: 295-310.
4. Casas JG, Woscoff A. Giant pilartumor of the scalp. Arch Dermatol.1980; 116: 1395.
5. Ackerman AB, Viragh PA, Chongchitnant N. Proliferating follicularcystic neoplasm. In: Ackerman AB, Viragh PA, Chongchi-tnant N, editors.Neoplasms with follicular differentiation. Lea &Febiger: Philadelphia;1993. p. 553-70.
6. Lund HZ. Atlas of tumor pathology. Tumors of the skin. Armed Forces Institute of Pathology: Washington; 1957.
7. Mathis ED, Honningford JB, Rodriguez HE, Wind KP, Connolly MM, Podbielski FJ. Malignant proliferating trichilemmal tumor. 2001; 24: 351-3.
8. Weiss J, Heine M, Grimmel M, Jung EG. Malignant proliferating trichilemmal cyst. J Am AcadDermatol. 1995;32: 870-3.