Title: Case of A Rapidly Growing Glioma in Near Term Pregnancy: The Dilemma of Baby First or Tumor First?

Authors: Abhiruchi Patki, MD, PDCC, Anjali Savargaonkar, Vijay R Shrotey MD

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.64

Abstract

A 25 year old primigravida, with a history of 37 weeks of gestation, presented with a 7 day history of progressive left sided weakness. Radiological examination revealed a well defined lesion of 6.4×5×6.2 cm in the right frontoparietal region, with evidence of mass effect. After a detailed assessment of all the available options in timing of both surgeries and the nature of emergency, a plan was made to carry out caesarean section and craniotomy for tumour removal in one single sitting. An attempt to balance smooth induction as required in neuroanaesthesia and rapid sequence intubation as required in obstetric anaesthesia was made.

Keywords: Pregnancy, Brain tumour, glioma, caesarean section.

References

1.      Wang L, Paech M. Neuroanesthesia for the Pregnant Woman. Anaesth Analg 2008; 107(1):193-200

2.      Pliskow S, Herbst SJ, Saiontz HA,Cove H, Ackerman R. Intracranial meningioma with positive progesterone receptors.J Reprod Med 1995;40:154-6

3.      Giannini A,Bricchi M. Posterior fossa surgery in the sitting position in a pregnant patient with cerebellopontine angle meningioma.Br J Anaesth 1999;82:941-4

4.      Balki M, Manninen PH.Craniotomy for suprasellar meningioma in a 28-week pregnant woman without fetal heart monitoring.Can J Anaesth 2004;51:573-6

5.      Belfort MA, Took-Miller C, Allen JC, et al. Changes in flow velocity,  resistance indices, and cerebral perfusion pressure in the maternal middle cerebral artery distribution during normal pregnancy.Acta Obstet Gynecol Scand.2001; 80:104-12

6.      Vougioukas VI,Kyroussis G,Glasker S et al.Neurosurgical interventions during pregnancy and the puerperium: clinical considerations and management.Acta Neurochir(Wien) 2004;146:1287-92 

7.      Tewari KS, Cappuccini F,Asrat T,et al.Obstetric emergencies precipitated by malignant brain tumors .Am J Obstet Gynecol 2000;182:1215-21

8.      Sahu S, Indu Lata,Gupta D. Management of pregnant female with meningioma for craniotomy.J Neurosci Rural Pract 2010Jan-Jun;1(1):35-37

9.      Unterrainer AF, Steiner H, Kundt MJ  Caesarean section and brain tumour resection Br J Anaesth 2011 ;107(1) :111-112

10.  S Santra, B Das. Effect of propofol and thiopentone on intracranial pressure and cerebral perfusion in patients undergoing elective craniotomy-a comparative study. Indian J Anaesth 2007;51(3):211-5

11.  Koerner IP, Brambrink AM. Brain protection by anaesthetic agents. Current Opin Anaesthesiol 2006;19:491-6

12.  Glosten B Anesthesia for Obstetrics. In: Miller RD ed.Anesthesia 5th edn. Philade-lphia: Churchill Livingstone,2000:2024-68

13.  Thomas JS, Koh SH, Cooper GM. Haemodynamic effects of oxytocin given as i.v.bolus or infusion on women undergoing Caesarean section.Br J Anaesth 2007;98:116-9

14.  Kitaguchi K, Nakajima T,Takaki O et al. The change in cerebral blood flow during hypotensive anaesthesia induced by prosta-glandin E1.Masui 1992;41(5):766-71

15.  Ross MG, Leake RD, Ervin MG et al. Fetal lung fluid response to maternal hyperosmolality. Paediatr Pulmonol 1986; 2:40-3.

Corresponding Author

Abhiruchi Patki, MD, PDCC

Associate Professor, Department of Anaesthesiology,

Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana State