Title: Autoimmune Hypothyroidism and Vitamin D Levels
Authors: Dr Ritu Priya, Dr Pramila Kalra, Dr Vasudha K C
DOI: http://dx.doi.org/10.18535/jmscr/v4i2.57
Objectives: Hypothyroidism is one of the commonest endocrine disorders. Autoimmunity has an important role in its etiology. The immunomodulatory role of vitamin D is emphasized in recent years. Vitamin D insufficiency/deficiency is seen to be associated with many autoimmune diseases like multiple sclerosis, SLE, Type 1 DM etc. This study was aimed to see the relation between serum vitamin D levels and serum TPO Ab levels in hypothyroid disease. Materials and Methods: Serum vitamin D (25-OH) levels were measured in 25 patients with autoimmune positive hypothyroidism and 27 healthy subjects, utilizing the ELISA method (Calbiotech diagnostics, USA). Vitamin D deficiency was designated at levels lower than 20 ng/ml. Antithyroid peroxidase antibodies were assayed by ELISA. TSH, T3, T4 levels were evaluated in all patients. 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