To Study Clinical Profile of Tuberculosis in Patients of Diabetes Mellitus

Title: To Study Clinical Profile of Tuberculosis in Patients of Diabetes Mellitus

Authors: Dr Ritu Gupta, Dr Sandeep Singh, Dr Mahesh Vijay Bodkhe

DOI: http://dx.doi.org/10.18535/jmscr/v4i2.50

Abstract

Diabetes mellitus is an independent risk factor for lower respiratory tract infections. Patients with diabetes are at greater risk of contracting tuberculosis, and diabetes can worsen the course of tuberculosis. Hyperglycemia appears to be a contributory factor to the development of pulmonary tuberculosis in diabetic patients. Complications related to uncontrolled blood sugar level are high in patients with tuberculosis. Also tuberculosis affects the effective control of blood sugar in diabetic patients requiring increase need of OHA and insulin. So both diseases have add on effect on others, pathogenicity control and management.

Results: Total 150 cases of diabetes mellitus taken.Maximum patients belong’s to age group >60 yrs in non-tuberculosis & 51-60 years in tuberculosis group; Male are More affected than Female. Most Common symptom was chest pain (29.62%) in patients of diabetes without tuberculosis may be due to older age group whereas anorexia (100%) was most common symptom in patients of tuberculosis with diabetes. When we compare clinical profile of diabetic patients it was found thatpulse rate is high , systolic and diastolic blood pressure was found to be significantly lower, mean PPBS (290.24 mg%) higher, total cholesterol lower, weight & BMI significantly lower in tubercular group. In clinical profile of diabetes with tuberculosis patients among all the studied parameters total cholesterol, LDLc and weight was found to be significantly lower in pulmonary as compared with extra pulmonary tuberculosis. Complications like retinopathy, neuropathy, nephropathy and other macrovascular complications are more in tubercular group but difference in retinopathy statistically significant .Chest radiograph revealed that 11.76% of patients had unilateral & 70.58% had bilateral lesions in which predominant lesion in middle & lower zone i.e 41.17% .Cavity noted in 17.60%.

Keywords: OHA: Oral hypoglycaemic agents, HIV: Human immunodeficiency virus, CSF: Cerebrospinal fluid, PPBS: Post prandial blood sugar, LDLc: Low density lipoprotein’s.

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Corresponding Author

Dr Ritu Gupta

W/O Dr Amit Gupta, 207, Ravindra Nagar

Adhartal, Jabalpur (M.P), Pin: 482004

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