Title: Neuropsychiatric Manifestations as the Presentation of Addison’s Disease Masquerading the Illness
Authors: Abiramy.S.P., Vengadakrishnan.K
DOI: http://dx.doi.org/10.18535/jmscr/v4i2.13
Adrenal insufficiency may present acutely as adrenal crisis or with chronic nonspecific symptoms, which requires a great deal of clinical suspicion. Adrenal insufficiency may also manifest with psychiatric manifestations, which makes its diagnosis even more challenging. The neuropsychiatric aspect of this condition is not fully understood. Patients with psychiatric symptoms are usually screened for other organic causes and are labeled as having mental disturbance. Neuropsychiatric symptoms could be the first presentation of Addison’s disease. We present a 38 year old female who initially presented with vomiting and altered behavior, subsequently diagnosed to have hypopituitarism. Keywords: Addison’s disease, Hypopituitarism, Neuropsychiatric manifestations, Anglin RE, Rosebush PI, Mazurek MF - The neuropsychiatric profile of Addison's disease: revisiting a forgotten phenomenon. Journal of neuropsychiatry and clinical neurosciences 2. CM Brosnan, NFC Gowing , Lesson of the Week: Addison's disease, British Medical Journal 1996 - bmj.com 312.7038.1085 3. Smith, Kent C. M.D.; Barish, Joel M.D.; Correa, Javier M.D.; Williams, Robert H. M.D. , Psychiatric Disturbance in Endocrinologic Disease, Journal of psychosomatic medicine, January 1972 - Volume 34 - Issue 1 4. E. Ur, T. H. Turner, T. J. Goodwin, A. Grossman, G. M. Besser, Mania in association with hydrocortisone replacement for Addison's disease, Postgrad Med J 1992;68:41-43 5. Behavioral Disturbances Associated with Endocrine Disorders, Annual Review of Medicine, Vol. 37: 205-214 (Volume publication date February 1986) 6. R Baschetti , Chronic fatigue syndrome: a form of Addison's disease - Journal of internal medicine, 2000 - Wiley Online Library 7. Varadaraj, R.; Cooper, A. J., Addison's disease presenting with psychiatric symptoms, The American Journal of Psychiatry, Vol 143(4), Apr 1986, 553-554. 8. Anders F. Thomsen , Tine K. Kvist, Per K. Andersen, Lars V. Kessing, The risk of affective disorders in patients with adrenocortical insufficiency, Psychoneuro-endocrinologyVolume 31, Issue 5, June 2006, Pages 614–622Abstract
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