Thyroid Dysfunction and Pregnancy Outcome in Indian Women

Title: Thyroid Dysfunction and Pregnancy Outcome in Indian Women

Authors: Dr Manisha Chauhan, Dr Saurabh Tomar

DOI: http://dx.doi.org/10.18535/jmscr/v4i3.60

Abstract

Objective: Development of maternal thyroid disorder during early pregnancy can influence the pregnancy outcome and fetal development. There is lack of published reports regarding relation of thyroid dysfunction with pregnancy outcome. The purpose of this study is to estimate the prevalence of thyroid dysfunction during pregnancy and To study the effect of thyroid dysfunction on pregnancy outcome.

Materials and Methods: The study was a prospective study with a sample size of 400 antenatal patients attending OPD and emergency ward. After taking consent, these patients were randomly selected for the study.

Results: The prevelance of thyroid disorders in our study was 12.5%.with subclinical hypothyroidism (7%), overt hypothyroidism (4%),subclinical hyperthyroidism (1%),overt hyper(0.5%).In our study subclinical hypothyroidism was associated with complications like PE(10.7%), AP(3.57%), PTD(10.7%), Severe Anemia (25%), IUGR (3.75%), LBW(10.75%).Overt hypothyroidism was associated with PE(18.7%), AP (6.25%), PTD (12.5%), Severe Anemia (31.25%), IUGR (12.5%), LBW(18.7%).

Conclusion: Prevelance of thyroid disorders especially subclinical hypothyroidism and overt hypothyroidism was high. Significant adverse effect on maternal and fetal outcome were seen emphasizing the importance of routine antenatal thyroid screening.

Key Words: Pre eclampsia (PE),Abruptio placentae (AP),Pre Term Delivery(PTD),Intra Uterine Growth Retardation (IUGR),Low Birth Weight(LBW),Still Birth(SB),Confidence Interval(CI).

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Corresponding Author

Dr Manisha Chauhan

M.D Genaral Medicine, SR,G.R. Medical College, Gwalior (MP)

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