Title: Diurnal Variation of Peak Expiratory Flow Rate in Healthy Young Adults of North East of India
Authors: Wasima Jahan, Pranjal Bhuyan, Rwitusmita Bharali
DOI: http://dx.doi.org/10.18535/jmscr/v4i3.31
PEF measurement is a simple and easy procedure to evaluate and assess the degree of 24hrs variation (circadian) in lung function. Thus this study was undertaken to study the diurnal variation in peak expiratory flow (PEF) in 60 healthy non-smoking adults of Northeast, in the age group between 18-24 years. The PEFR (L/min) was measured with mini Wright’s peak flow meter for three times a day, morning, afternoon and evening. The diurnal variation was observed with lowest values in the morning followed by progressive rise peaking in the evening. Diurnal variation for individual subject was calculated by using amplitude percent mean (A%M). We conclude that a definite pattern of diurnal variation in PEF is seen in healthy population and its knowledge is important for meaningful interpretation of PEF recordings in disease condition. Key words: Peak expiratory flow, diurnal variation 1. American thoracic society. standardisation of spirometry:1994 update. Am J Respir Crit Care Med 1995;152:1107-1136 2. Higgins BG,Britton JR, Chinn S,et al.The distribution of peak expiratory flow variability in a population sample.Am Rev Respir Dis 1989;140:1368-1372 3. A.N.Aggarwal,D.Gupta,S.changanti and S.K Jindal, Diurnal variation of peak expiratory flow rate in healthy young adults. The Indian journal of Chest Disease and allied sciences,2000,vol 42:15-19. 4. Quackenboss JJ,Lebowitz MDet al.The normal range of Diurnal changes in peak expiratory flow rate: Relationship to symptoms and respiratory disease Am Rev Respir Dis 1991;143:323-330 5. Casale R,Pasqualetti P.Cosinor analysis of circadian peak expiratory flow variability in normal subjects,passive smokers,heavy smokers, patients with chronic obstructive pulmonary disease and patients with interstitial lung disease.respiration 1997; 64:251-256 6. Zureik M,Liard R,Segala C,Henry C et al: peak expiratory flow variability in population survey: Does the number of assessment matter? Chest 1995,107:418-423 7. Hetzel MR, Clark TJH. Comparison of normal and asthmatic circadian rhythm in peak expiratory flow rate.thorax 1980;35:732-738. 8. Higgins BG, Britton JR, Chinn S, Lai KK, Burney PG, Tattersfield AE. Factors affecting peak expiratory flow variability and bronchial reactivity in a random population sample. Thorax 1993; 48: 899–905. 9. Goval M, Goel A, Kumar P, Bajpai M, Verma NS, Kant S, Tiwari S. Circadian rhythm of peak expiratory flow rates in healthy north Indian men. Indian J Physiol Pharmacol 2008;53:64-8.Abstract
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