Why is HIV/AIDS so hard to treat?

Title: Why is HIV/AIDS so hard to treat?

Authors: Dilip D. Karad, Dr. Arun S. Kharat*

DOI: http://dx.doi.org/10.18535/jmscr/v4i4.49

Abstract

The HIV/AIDS is a global pandemic and remains the world’s leading infectious killer. Death of HIV/AIDS patients worldwide is a powerful reminder that there is no cure for HIV/AIDS. However, Anti Retroviral drug treatment can slow down the course of disease and may lead to near normal life expectancy. But HIV drug resistance highlights the need for new and more powerful drugs. Across the globe, researchers are working hard to make an HIV vaccine. Gene editing to prevent HIV is innovative hypothesis to prevent HIV/AIDS which has generated hope to prevent and cure it.

References

1. UNAIDS. United Nations Programme on HIV and AIDS. (2015). http://www. unaids. org/en/resources/campaigns/How AIDS changed everything/factsheet

2. Karad D, Kharat A (2015) Seroprevalence of Torch Infections in Bad Obstetrics History in HIV and Non-HIV Women in Solapur District of Maharashtra India. J Hum Virol Retrovirol 2(7): 00067. DOI: 10.15406/jhvrv.2015.02.00067

3. Dutta A, Barker C, Kallarakal A.(2015). The HIV Treatment Gap: Estimates of the Financial Resources Needed versus Available for Scale-Up of Antiretroviral Therapy in 97 Countries from 2015 to 2020. PLoS Med. 2015 Nov 24;12(11): e1001907; discussion e1001907. doi: 10.1371/journal.pmed.1001907. eCollection 2015. PMID: 26599990 PMCID: PMC4658189

4. Hai-Bo Wang, Qiu-Hua Mo, and Ze Yang (2015) HIV Vaccine Research: The Challenge and the Way Forward. J Immunol Res. 2015; 2015: 503978. Published online 2015 Mar 15. doi: 10.1155/2015/503978 PMCID: PMC4377490

5. Gero Hütter, , Daniel Nowak, Maximilian Mossner, B.S., Susanne Ganepola, Arne Müßig, et. al; (2009). Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation. N Engl J Med.; 360:692-698. DOI: 10.1056/ NEJMoa0802905.PMID: 19213682.

6. TAG, Treatment Action Group. (2015). Pipeline Reports. http://www.treatment-action group.org/pipeline-report.

7. Eholié SP, Aoussi FE, Ouattara IS, Bissagnéné E, Anglaret X. (2012). HIV treatment and care in resource-constrained environments: challenges for the next decade. J Int AIDS Soc. 2012 Aug 22;15(2):17334. doi: 10.7448/ IAS.15.2.17334. PMCID: PMC3494167

Corresponding Author

Dr. Arun S. Kharat

Department of Biotechnology, Babasaheb Ambedkar Marathwada University

Sub-campus Osmanabad, MS, India Pin: 413 501.

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Telefax: +91-240-2403335