Title: Study on Uropathogens with Antimicrobial Susceptibility Pattern in the Elderly at a Tertiary Care Hospital- Mangadu, South Chennai India
Authors: Dhevahi Elumalei, Sumathi.G., Sambandan A.P, Natrajan.V.S, Dinakaran.N
DOI: http://dx.doi.org/10.18535/jmscr/v4i4.11
Urinary tract infections (UTI) second most common cause of infectious disease among 65 yr older the elderly population (>65years) 1. Usually over diagnosed, treated on the basis of nonspecific clinical signs and symptoms. Elderly diagnosis always require the presence of new urinary symptoms, with or without systemic symptoms. Aim: Our study aims to describe the uropahogens, antimicrobial resistance rates among elderly patients attending our hospital near Mangadu South of Chennai. Study Subjects & Results: A total of 468 urine specimens were analysed from elderly patients above sixty years of age. 343 were culture positive. Antibiotic susceptibility pattern of these patients were analysed. Our study shows among the GNB the E.Coli as the commonest, followed by Klebsiella. Staphylococus aureus was seen in many of the elderly population among the cocci group. Amikacin, Levofloxacin, Gentamycin and Nitrofurantoin were effective for treatment of UTI. Evidence showed resistance to Ampicilliin, Co-trimoxazole, cephalosporins. Conclusion: study was able to standardize the pattern of antibiotic treatment within the elderly group after the analysis of antibiogram sensitivity. Keywords: urinary tract infection, elderly, Bacterial agents, Antimicrobial susceptibility 1. Urinary tract infection in old age: over- diagnosed and over-treated. Age Ageing. 2000;29:297–298. 2. Woodford HJ, George J. Diagnosis and management of urinary tract infection in hospitalized older people. J Am Geriatr Soc. 2009;57: 107–114. 3. Optimal management of urinary tract infections in older people Louise A Beveridge, Peter G Davey, et.al., Interv Aging. 2011; 6: 173–180 4. Urinary Tract Infections in Elderly Persons. Chapter 32: Manisha Juthani- Mehta et.al Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut 5. The Incidence of uropathogens and their resistance pattern in a tertiary care hospital R. Shyamala and Janardhan Rao Der Pharmacia Lettre, 2013, 5 (1):316-317 6. Urinary Tract Infections in Older Women: A Clinical Review Lona Mody et al.JAMA. 2014 February 26; 311(8): 844–854. doi:10.1001/jama.2014.303. 7. Infectious disease hospitalizations among older adults in the United States from 1990 through 2002.Curns AT, Holman RC, Sejvar JJ, Owings MF, Schonberger LB, Arch Intern Med 165: 2514–2520, 2005 8. Urinary Tract infection in old age: Over diagnosed and over treated –Commentary. Age and Aging 2000; 29;297- 298 9. Urinary Tract Infections in Older Women: A Clinical Review Lona Mody et al.JAMA. February 26; 311(8): 844–854. 10. Optimal management of urinary tract infections in older people Louise A Beveridge, Peter G Davey, et.al., Interv Aging. 2011; 6: 173–180. 11. Antimicrobial resistance in urinary pathogens among Swedish nursing home residents remains low: a cross-sectional study comparing antimicrobial resistance from 2003 to 2012 Sundvall et al. BMC Geriatrics 2014, 14:30 12. The Incidence of uropathogens and their resistance pattern in a tertiary care hospital R. Shyamala and Janardhan Rao Der Pharmacia Lettre, 2013, 5 (1):316-317 13. Urinary Tract Infection at the Age Extremes: Pediatrics and Geriatrics Linda M. Dairiki Shortliffe, et., al. July 8, 2002 The American J Med. Volume 113 (1A) 57S 14. Antimicrobial resistance in urinary pathogens among Swedish nursing home residents remains low: a cross-sectional study comparing antimicrobial resistance from 2003 to 2012 Sundvall et al. BMC Geriatrics 2014, 14:30 Abstract
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