Title: Study on ECG Changes in Chronic hypertensive Patients in a Medical College Hospital of Odisha
Authors: Dr Sudipto Modak, Dr Poonam Mehta, Dr Jyotsnarani Patnaik
DOI: http://dx.doi.org/10.18535/jmscr/v4i5.14
Aims: Aim of this study was to analyze and compare the variations and abnormalities in ECG wave forms among people with chronic hypertension and controls. Methods: The study was conducted in Hi-Tech Medical College & Hospital, Bhubaneswar during the period from Sept 2013 – Aug 2015. The study included 50 people with chronic hypertension and 50 controls, each between ages 40-70 years from general population, and also from Medicine outpatient department, HMC&H, Bhubaneswar. Following an explanation about the nature and purpose of study, those subjects who are willing to participate where included after obtaining their consent. Subjects with exclusion criteria were dropped. Detailed history from subjects, blood pressure (sitting position) and electrocardiogram was recorded during resting state in supine position. The ECG results were evaluated for parameters like heart rate, P wave, PR interval, QRS complex, QRS axis, QT interval, QTc interval, ST segment and T wave Results: There was statistically significant increase in QT interval & QTc interval in chronic hypertensives than controls. There was increased occurrence of LVH, ST depression and T wave inversion in chronic hypertensives than controls. Conclusion: This study shows that chronic hypertension is associated with QT prolongation. Most frequently occurring ECG abnormalities in chronic Hypertension are LVH, ST depression and T wave inversion. Keywords: Chronic hypertension; left ventricular hypertrophy, QT prolongation, ST depression, T wave inversion. 1. Vasan RS, Larson MG, Leip EP, et al: Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 2001; 345:1291-7. 2. Stamler J, Stamler R, Neaton JD: Blood pressure, systolic and diastolic, and cardiovascular risks: U.S. population data. Arch Intern Med 1993; 153:598-615. 3. Yusuf S, Hawken S, Ounpuu S, et al: Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Casecontrolstudy. Lancet 2004; 364:937-52. 4. Dannenberg AL, Garrison RJ, Kannel WB: Incidence of hypertension in the Framingham Study. Am J Pub Health 1988; 78:676-9 5. 2006 Jan 3;113(1):67-73. Epub 2005 Dec 19.Electrocardiographic strain pattern and prediction of new-onset congestive heart failure in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study.Okin PM, Devereux RB, Nieminen MS, Jern S, Oikarinen L, Viitasalo M, Toivonen L, Kjeldsen SE, Dahlöf B; LIFE Study Investigators. 6. J Hypertens. 1998 May;16(5):681-8.Prevalence of episodes of ST-segment depression among mild-to-moderate hypertensive patients in northern Italy: the Cardioscreening Study. Stramba-Badiale M, Bonazzi O, Casadei G, Dal Palù C, Magnani B, Zanchetti A. 7. Blood Press Monit. 2003 Feb;8(1):45-51.Silent myocardial ischaemia in treated hypertensives with and without left ventricular hypertrophy. Stojanovic MM, O'Brien E, Lyons S, Stanton AV. 8. AnadoluKardiyol Derg. 2002 Jun; 2(2):121-9; AXVII.Arrhythmia risk and noninvasive markers in hypertensive left ventricular hypertrophy] Akdeniz B, Güneri S, Badak O, Aslan O, Tamci B.Abstract
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