Title: The Prevalence of Shigella and Enterotoxigenic E. Coli Infection amongst Patients Attending a General Hospital, North Bank Makurdi Nigeria
Authors: Agbulu, C. O, Okoko, J. A, Adokwu, .E. E
DOI: http://dx.doi.org/10.18535/jmscr/v4i5.11
The prevalence of Enterotoxigenic E. coli and Shigella spp infection was conducted at General Hospital Makurdi, Benue State, Nigeria. One hundred and eight (108) fecal specimens from consenting clinically diagnosed patients from both sexes and of all age groups were collected. Each feacal sample was inoculated onto Salmonella Shigella agar (SSA agar) and Triple sugar iron agar (TSIA). Media were incubated at 37oc for 24 hr. Isolates were identified using standard microbiological techniques. For the study data, Chi-square (χ2) or Fisher’s exact test as appropriate and odd ratio analysis were used for analysis. The prevalence of Enterotoxigenic E. coli and Shigella spp from the sample collected was 12.5% each. Favorable factors found to be associated with infection included the wetter seasons of the year and asymptomatic carriage of infection. Gender is not a statistically significant (p˃ 0.05) risk factor of infection in this study. There was a strong evidence of relationship between bacteria isolate and source of drinking water of the feacal sample. This suggests that it is necessary to drink safe and purified water free from pathogenic organisms as well as washing hands with antibacterial soap after going to the toilet or shaking hands since it can be a source for the transfer of bacteria from one person to the other. Keywords: Enterotoxigenic E.coli ,Shigella spp,General Hospital Makurdi 1. Ashkenazi, S., Levy, I., Kazaronovski V. (2003). Growing antimicrobial resistance of Shigella isolates. J Antimicrob Chemother 51:427-429 2. Beatty, M.E., Adcock, P.M., Smith, S.W. (2006). Epidemic diarrhea due to enterotoxigenic Escherichia coli. Clin Infect Dis; 42:329. 3. Belongia, E. A., Osterholm, M.T., Soler, J.T., Ammend, D.A., Braun, J.E. and Macdonald, K.L. (1993). Transmission of Escherichia coli O157: H7 infection in Minnesota child day-care facilities JAMA. 289: 883-888. 4. Bennish, M.L, Wojtyniak, B.J. 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