Title: Echocardiographical Evaluation And Cardiovascular Changes In Chronic Obstructive Pulmonary Disease Patients In Tertiary Care Hospital
Authors: Saurabh, Lalit Singh, Anurag Agarwal, Rajeev Tandon, Hemant kumar
DOI: http://dx.doi.org/10.18535/jmscr/v4i6.77
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a disease characterized by progressive poorly reversible airway destruction. Cardiovascular disease accounts for significant morbidity and mortality in chronic obstructive pulmonary disease (COPD). Its prevalence and mechanisms of association have not been elucidated. The study aimed to assess the prevalence of echocardiographic abnormalities and potential risk factors in patients with COPD. MATERIALS AND METHODS: A total of 86 COPD patients were enrolled in the present study. All patients were subjected to full medical history and clinical examination, chest radiography, complete blood count, lipid profile, spirometry, 2D-echocardiography. RESULTS: 86 patients included in our study. Out of 86 patients, 74( 86%) were male and 12 ( 14 %) were females. Male to female ratio was 6.1:1. Mean age was 58.2 ± 12.7 years. Severity of COPD patients classify according to GOLD criteria. Out of 86 patients, 15 patients had FEV1< 80% of predicted, 10% patients had mod.(FEV1 50-80 %), 24 had severe and 37 had very severe disease. Pulmonary artery hypertension was defined as SPAP> 30 mmHg which was seen in 40 cases (46.5%) . Out of 50 patients, 15 (17.4%) patients had mild, 5 (10.5%) had moderate and 18 (18.6%) had severe pulmonary hypertension, 12 (13.6%) patients had right ventricular systolic dysfunction, 11 (12.8%) had left ventricular systolic dysfunction and left ventricular hypertrophy. 16 ( 18.6%) had cor pulmonale. CONCLUSION: Echocardiography is helpful in early detection of cardiac complication in COPD patients. KEY WORDS: Chronic obstructive pulmonary disease , pulmonary hypertension, cor pulmonale, left ventricular hyperterophy. 1. Murray CJ, Lopez AD: Alternative projections of mortality and disability by cause 1990- 2020: Global Burden Disease Study. Lancet , 1997; 349: 1498-1504. 2. World Health Report, World Health Organization, Geneva. 2000. 3. 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