Title: Role of Aging, Hypertension and Dyslipidaemia in Carotid Intimal Medial Thickness among Patients with Ischemic Stroke Proven By Computed Tomography
Authors: Dr Sangram S Mangudkar, Dr Kiran Shinde, Dr Gajanan D Khadkikar, Dr Jyoti A Landge
DOI: http://dx.doi.org/10.18535/jmscr/v4i6.69
Background: Cerebrovascular accident or stroke is defined by an abrupt onset of neurological deficit that is attributable to a focal vascular cause. This may result from brain infarction or hemorrhage. Carotid intimal-medial thickness (IMT) predicts future vascular events in the general population. Most scientists studying the relation of intimal medial thickness with atherosclerosis have concentrated their efforts on coronary artery disease with less data available on the relation between intimal medial thickness and stroke, Present study was carried out to study the association of an increase in carotid artery intimal-medial thickness with aging, hypertension and dyslipidaemia in patients with ischemic stroke proven by computed tomography. Material and methods: A cross sectional study of 106 pateints fulfilled with inclusion criteria was carried out in dept of general medicine at Dr D Y Patil Medical College, pimpri, Pune. Informed consent was taken from patients, they underwent history taking, proper clinical examination, radiological and biochemical investigations Collected data entered in excel and results were analyzed using Chi-square test & Independent Sample “T test” in SPSS 20. Result: out of 106, the largest group was in the age range of 60 – 70 years, mean age of 61 years with range of 23- 83 years. There were 69 males (65%) and 37 females (35%) in the study. Hypertension (60%) was the most common risk factor, other common risk factors being smoking (24%), and ischemic heart disease (20%). Conclusion: The study showed old age, hypertension, dyslipidaemia is associated with ischemic stroke by increasing carotid intimal-medial thickness (IMT). Keywords: Dyslipidemia, Hypertension, Ischemic stroke, Intimal-medial thickness 1. Uma N, Chugh SK, Harshwardhan, Geol A, Gopal D.Echocardiography in patients with cerebral infarction. JAPI 1999; 47: 291–293. 2. 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