Title: A Comparative Study of Vitamin D and Serum Total Calcium Levels in Two Socioeconomic Groups in Guwahati Metropolitan City
Authors: Dr Dibyaratna Patgiri, Dr Syeda Mohsina Rohman, Dr Mousumi Borgohain Borah
DOI: http://dx.doi.org/10.18535/jmscr/v4i6.57
The aim of this cross-sectional study was to assess the Vitamin D and Total Calcium levels among two socio-economic groups in the city of Guwahati. The study included 180 participants divided equally into two groups – Office group and Wage-earner group. Serum Vitamin D was assessed by ELISA using BIORAD microplate reader and Serum Calcium by spectrophotometry using Vitros 5600 Fully autoanalyzer. Unpaired t-test results showed statistically significant decreased levels of both Vitamin D and Total Calcium in individuals in the Office group as compared to those in the Wage-earner group (p < 0.05). Females, irrespective of the group, had statistically significant lower levels of both Vitamin D and Total Calcium as compared to males (p < 0.05). The study concludes that lifestyle factors related to work are affecting the Vitamin D status in the population and that Vitamin D insufficiency and deficiency is more prevalent among females. Key words: Vitamin D, Total Calcium, Sunlight exposure. 1. Bender DA. Ch 44, Micronutrients: Vitamins and Minerals. In: Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA, editors. Harper’s Illustrated Biochemistry. 29th ed.,New York; McGraw-Hill Medical; 2009, p. 525-42. 2. Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int, 2009 Nov;20(11):1807-20. 3. Londhey V. Vitamin D Deficiency: Indian Scenario. JAPI, 2011 Nov;59:695-96. 4. Rathi N, Rathi A. Vitamin D and Child Health in the 21st Century. Indian Pediatrics, 2011 Aug;48:619-25. 5. Bringhurst FR, Demay MB, Kronenberg HM. Ch 28, Hormones and Disorders of Mineral Metabolism. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, editors. Williams Textbook of Endocrinology. 12th ed.; Philadelphia; Elsevier Saunders; 2011, p. 1237-1304. 6. Martini LA, Verly E, Marchioni DML, Fisberg RM. Prevalence and correlates of calcium and vitamin D status adequacy in adolescents, adults, and elderly from the Health Survey - Sao Paulo. Nutrition, 2013; 29:845–850. 7. Holick MF. Vitamin D: Important for Prevention of Osteoporosis, Cardiovascular Heart Disease, Type 1 Diabetes, Autoimmune Diseases, and Some Cancers. Southern Medical Journal, 2005 Oct;98(10):1024-27. 8. Vit d 9. VITROS Chemistry Products Ca Slides. REF 145 0261. [products insert]. Ortho-Clinical Diagnostics, Inc. document: Pub. No. MP2-10 Version 7.0. 10. Vierucci F, Pistoia MD, Fanos M, Erba P, Saggese G. Prevalence of hypovitaminosis D and predictors of vitamin D status in Italian healthy adolescents. Italian Journal of Pediatrics; 2014, 40:54. 11. Elsammak MY, Al-Wossaibi AA, Al-Howeish A, Alsaeed J. High prevalence of vitamin D deficiency in the sunny Eastern region of Saudi Arabia: a hospital-based study. Eastern Mediterranean Health Journal, 2011; 17(4):317-22. 12. Holvik K, Brunvand L, Brustad M, Meyer HE. Vitamin D status in the Norwegian population. In: Solar Radiation and Human Health. Espen Bjertness, editor. Oslo: The Norwegian Academy of Science and Letters, 2008. 13. Daly RM, Gagnon C, Lu ZX, Magliano DJ, Dunstan DW, Sikaris KA et al. Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population-based study. Clinical Endocrinology, 2012; 77:26–35. 14. Clemens TL, Adams JS, Henderson SL, Holick MF. Increased skin pigment reduces the capacity of skin to synthesis vitamin D3. Lancet, 1982; 1:74–75. 15. Heaney RP, Dowell MS, Hale CA, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr, 2003; 22:142–46. 16. Heaney RP. Vitamin D depletion and effective calcium absorption. A letter to the editor. J Bone Min Res, 2003; 18:1342 17. Pettifor JM. Vitamin D &/or calcium deficiency rickets in infants and children; a global prespective. Indian J Med Res, 2008; 127: 245-9.Abstract
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