Title: Utility of 99mTc DTPA Renogram in the evaluation of renal dysfunction associated with coronary artery disease in a hypertensive patient
Authors: Dr V. Sivasubramaniyan, Mr Adavala Jagadeesh, Prof. Dr K. Venkataramaniah
DOI: http://dx.doi.org/10.18535/jmscr/v4i6.38
Essential hypertension has adverse effects on both renal and heart function. There is an underlying relation between CKD (Chronic Kidney Disease) and CAD (Coronary Artery Disease).Patients with CKD has more severe CAD and prognosis of renal function is poor in patients with severe CAD. In the present study we are reporting the utility of 99mTc DTPA (diethylene triamine penta acetic acid) renogram in proving cardio renal association in a patient with AOE (angina on exertion) II, HTN (Hypertension) diagnosed with CAD by Tl-201 gated SPECT. Key-words: Essential hypertension, Coronary Artery Disease, Tc-99m DTPA renogram, Chronic Kidney Disease, cardio renal association. Key message: Tc-99m DTPA renogram successfully could identify the CKD in hypertensive patient diagnosed with CAD. 1. Krz esinski J M, Cohen EP. Hyper tension and the kidney. Act a Clin Belg. 2007 Jan-Feb; 62(1): 5-14. 2. Arihiro Kiyosue, Yasunobu Hirata, Jiro Ando, Hideo Fujita et.al. Relationship between Renal Dysfunction and Severity of Coronary Artery Disease in Japanese Patients. Circ J Vol.74, April 2010. 3. Coresh J, Astor BC, Greene T, Eknoyan G, et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third national health and nutrition examination survey. American Journal of Kidney Disease. 2003; 41 (1): 1-12. 4. Mark J. Sarnak, Andrew S.et.al. Kidney Disease as a Risk Factor for Development of Cardiovascular Disease. Circ J 2003; 108:2154 –2169. 5. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351:1296 – 1305. 6. Mann JF, Gerstein HC, Pogue J, Bosch J, Yusuf S. Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: The HOPE randomized trial. Ann Intern Med2001; 134:629 – 636. 7. Fukuta H, Ohte N, Mukai S, Asada K, Wakami K, Goto T.et al. Relationship between renal function, aortic stiffness and left ventricular function in patients with coronary artery disease. Circ J 2009; 73:1740 – 1745. 8. Levey AS, Coresh J, Balk E et al. National Kidney Foundation Practice Guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med 2003; 139: 137–147Abstract
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