Title: Clinico Pathological Evaluation of Benign and Malignant Soft Tissue Tumors-2 Years Retrospective Study
Authors: Dr Byna Syam Sundar Rao, Dr Bhavana Grandhi, Dr Vissa Shanthi, Dr Vydehi Bheemaraju, Dr Nandam Mohan Rao, Dr Ankita Goel
DOI: http://dx.doi.org/10.18535/jmscr/v4i6.23
Background: Soft tissue tumors are a diverse and heterogeneous group of tumors. The incidence of benign soft tissue tumors are high relative to malignant tumors. The natural course of soft tissue tumors is un predictable and very aggressive if not diagnosed early. Histopathology is considered gold standard in diagnosing soft tissue tumors Objective: To study the benign and malignant soft tissue tumors with respect to incidence of age, sex and site distribution and study of pathological features of soft tissue tumours. Materials and methods: Retrospective study was undertaken for a period of 2 years from Dec 2013 to Dec2015 in department of pathology, narayana medical college & hospital, Nellore, Andhra Pradesh, India. Results: 90 cases of soft tissue tumors recorded in the department of pathology in 2 years. Of all soft tissue tumors benign soft tumors formed 82 cases (89.1%) while malignant soft tissue tumours constituted 8cases (10.9%). The soft tissue tumors in general had slightly male predominance with 2.1:1 is male to female ratio. Commonest benign soft tissue tumor was lipoma and malignant soft tissue tumor was fibrosarcoma in our study. The common site of occurred ce of benign soft tissue tumors was Head & neck while for malignant soft tissue tumors was extremities. Benign soft tissue tumors were commonly affected in 2nd decade while for malignant tumors were commonly affected in 5th decade. Conclusion: The histopathological evalution is still the gold standard for the proper diagnosis of soft tissue tumors. Key words: Soft tissue tumors, benign, malignant, incidence. 1. Kransdorf MJ; Malignant soft tissue tumors in a large referral population; distribution of specific diagnosis by age,sex and location, AJR AMJ Roentgenol., 1995;164(1):129-134 2. Kransdorf MJ; Benign soft tissue tumours in a large referral population distribution of specific diagnoses by age, sex, and location. AJR Am J roentgenol MJ; 1995; 164(2) : 395-402 3. Kasraeian S,Allison,DC,Ahlmann ER, Fedenko AN,Menendez LR;A comparision of Fine needle aspiration,core biopsy,and surgical biopsy in the diagnosis of extremity soft tissue mass.clin ortho Relat Res.,2010;468:2992-3002. 4. Enzinger F.M& Weiss S.W. soft tissue tumours st.louis . The CV mosbyco 1988. 5. Myhre, Jenson o etal. Histopathological staging in soft tissue tumours in relation to in 261 surgically treated patients. Acta pathol, microbial. Immunol seana (A)91:145 6. Angervall L ETAL. The diagnosis and prognosis of soft tissue tumors semin diagn. Pathol 3:240. 7. Pramila Jain, Archana Shrivastava,Reeni Malik. Clinicomorphological Assessment of soft tissue tumors. Sch.J. App.Med.Sci,2014;2(2D):886-890. 8. M.Janaki, K..V ijaya satish Arora, Swarooparani, M.Phani Kumar,Sandhya krupal.Morphological study of soft tissue tumors.IJRHS,april-jun 2015,vol-3,issue-2:364-368. 9. costa.J.etal. The grading of soft tissue sar comas . Results of a clinicopathological correlation in a series of 163 cases. Cancer 1984;53;530 10. Rydholm A Berg. No. size, site & Clinical incidence of lipomas. Factors in differential diagnosis of lipoma and sarcoma. Act Orthop seand 54:929, 1983 11. Bharti G Ramnani,Ashutosh kumar,Shruti Chandak,Amar Ranjan, AND Mehul kumar Patel.clinico pathological profile of Benign soft tissue tumors: A study in a Tertiary care hospital in western India,journal of clinical diagnostic research 2014 oct:8(10):1-7 12. Gabhane sushma K , etal . Morphological spectrum of peripheral nerve sheath tumours : A series of 126 cases. IAPM.2009; 52;(1);29-33 13. Manuel Riveros.The glomus tumors reports of 20 cases.Am.surg.1951;133:394 14. Darwish FM,Haddad WH.Giant cell tumor of tendon sheath:experience with 52 cases.Singapore MED J.2008;49(11):879-82. 15. Calonje E,et al.Cellular benign fibrous histocytoma.clinicopathological analysis of 74 cases of a distinctive variant of cutaneous fibrous hiscytoma with frequence recurrence. Am J Surg Pathol. 1994;18(7):668-76. 16. Wibmer C, Leithner .A, zielanke n, sperd M, windhager R . Increasing incidence rates of soft tissue sarcomas? A population based epidemiological study and literature review. Ann on col . 2010;21(5):1106-11 17. Mandong BM,Kidmas AT,Manasseh AN, Echejoh GO,Tanko Madaki AT; Epidemiology of soft tissue sarcomas in jos,North central ,Nigeria.Niger j Med, 2007;16(3):246-249 18. Abudu EK,AKinde OR,Oyebadejo TO, Efunshile AM,Musa OA,Banjo AA: Histopathological study of soft tissue malignancies in a teaching hospital, sagamu, South-west Nigeria. Nig Q J Hosp Med;2010;20(1):42-45. 19. Pritchard DJ etal.Clinico pathological & statistical study of 199 tumors of soft tissues. cancer 33:888,1974 20. Gutirez.G tal. Dermatofibrosarcoma protruberans -review of 30 cases Int.j. Dermat US 1984 21. Leslie A et al.Histologic features relating to prognosis in synovial sarcoma.cancer 59:1810-1814,1987.Abstract
References