Title: A Study of Relationship between Serum Lipids and Sensorineural Hearing Loss

Authors: Dr Anil.H.T, Dr Shazia

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i7.65

Abstract

Objectives: To study the correlation between sensorineural hearing loss and serum level of total cholesterol, triglycerides, HDL (High Density Lipoprotien) and LDL (Low Density Lipoprotien) in patients aged between 30 to 60 years attending otorhinolaryngology department of KIMS.

Materials and methods: 100 adults aged 30-60 years, with SNHL were included in a prospective comparative study and various degree of hearing loss was compared with serum lipids level. Relevant history was obtained. Examination and investigations were conducted.

Results: Statistically significant(p<0.05)mean values of total cholesterol, triglycerides among different degrees of SNHL were found out to be directly proportional in both sexes. In contrast mean values of HDL was inversely proportional.

Conclusion: The study shows significant relationship between serum lipid and various degrees of sensorineural hearing loss. Increase in total cholesterol, triglycerides and LDL, were associated with worsening of hearing levels. Elevated levels of HDL were found to be associated with better hearing levels. Early detection can prevent high risks for both coronary artery disease, hearing loss and vestibular dysfunction.

Keywords:  Hearing loss, Total Cholesterol, Triglycerides, LDL, HDL.

References

 

1.      Suzuki K, Kaneko M, Murai K. Influence of serum lipids on auditory function. The Laryngoscope. 2000 Oct 1;110(10):1736-8.

2.      Lee FS, Matthews LJ, Mills JH, Dubno JR, Adkins WY. Analysis of blood chemistry and hearing levels in a sample of older persons. Ear and hearing. 1998 Jun 1;19(3):180-90.

3.      Jones NS, Davis A. A prospective casecontrolled study of patients presenting with idiopathic sensorineural hearing loss to examine the relationship between hyperlipidaemia and sensorineural hearing loss 1. Clinical Otolaryngology & Allied Sciences. 1999 Dec 1;24(6):531-6.

4.      Spencer JT. Hyperlipoproteinemias in the etiology of inner ear disease. The Laryngoscope. 1973 May 1;83(5):639-78.

5.      Expert Panel on Detection E. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Jama. 2001 May 16;285(19):2486.

6.      Friederich G, Pilger E. Lipoproteins in cochleovestibular disorders. Arch Otolaryngol. 1981;232:101-5.

7.      Gates GA, Cobb JL, D'Agostino RB, Wolf PA. The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors. Archives of Otolaryngology–Head & Neck Surgery. 1993 Feb 1;119(2):156-61.

8.      Saito T, Sato K, Saito H. An experimental study of auditory dysfunction associated with hyperlipoproteinemia. Archives of oto-rhino-laryngology. 1986 Sep 1;243(4):242-5.

9.      Gratton MA, Wright CG. Alterations of inner ear morphology in experimental hypercholesterolemia. Hearing research. 1992 Aug 1;61(1-2):97-105.

10.  Ullrich D, Aurbach G, Drobik C. A prospective study of hyperlipidemia as a pathogenic factor in sudden hearing loss. European archives of oto-rhino-laryngology. 1992 Jan 1;249(5):273-6.

Corresponding Author

Dr Shazia

Junior Resident, Department of ENT, KIMS Hospital,

Kempegowda Institute Of Medical Sciences,

K.R Road, V.V Puram, Bangalore- 560004 Karnataka, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Contact No: +917022140188