Title: Study of Socio- Clinical Profile and Aetiology of Pleural Effusion
Authors: Dr Gursimran Singh, Dr Jyoti Landge, Dr Harpreet Singh
DOI: http://dx.doi.org/10.18535/jmscr/v4i7.31
Introduction: Pleural effusion is an abnormal, collection of fluid in pleural space resulting from excess of fluid production or decreased absorption. Exudates are produced by variety of inflammatory conditions and require more extensive evaluation and treatment than transudates. Laboratory testing (albumin, glucose, pH, LDH, cell counts) helps to reach the aetiology of pleural exudates. Present study was conducted to find out socio-clinical profile of plural effusion and to find out aetiology by using various laboratory tests. Aims and Objectives: To study socio-clinical profile and aetiology of pleural effusion. Material and Methods: Descriptive and Cross sectional study was conducted in Dept. of General Medicine, Dr. D.Y. Patil Medical College, Pune from Sept 2013 to Aug2015.Institute Ethics committee approvals obtained before the start of study. Total 50 cases were collected by convenient sampling method. Age more than 15years were included. Patients on AKT or ART, Age less than 15 years, pregnant women, post traumatic effusion and critically ill patients of pleural effusion on ventilator were excluded from study. Results: Maximum 29(58%) patients were in age group of 30-45 years, M:F= 2.3:1. Mean age was 37.34years and in range of 17-67years. More commonly presenting symptoms were pain in chest, fever and dyspnoea. Typical features of pleural effusion i.e. diminished movements, dull percussion note and absent breath sounds were observed in 40 (80%). Out of 50 cases 30 were exudative pleural effusion, and maximum 18 cases out of 30 were Tuberculosis as a cause for pleural effusion. Keyword: Clinical profile, aetiology, Pleural effusion 1. GilSuayV,Martínez Moragón E,Cases Viedma E, Perpiñá Tordera M, León Fábregas M,Sanchis AldásJ. Pleural cholesterol in differentiating transudates and exudates. A prospective study of 232 cases. Respiration.1995;62(2):57-63. 2. MitrouskaI, BourosD.The trans-exudative pleural effusion. Chest.2002;122(5):1503–5. 3. McGrath E E, Anderson P B. Diagnosis of Pleural Effusion: A Systematic Approach. AmJ Crit Care 2011;20(2):119-28. 4. Light RW. Pleural effusions .Med Clin North Am.2011;95:1055–1070. 5. Light RW. Pleural diseases.6th ed. Philadelphia: Lippincott Williams& Wilkins;2013. 6. Light RW. Pleural Disease, 4th ed. Philadelphia: Lippincott Williams, Wilkins, 2001. 7. Valdés L, San José E, Alvarez D, Sarandeses A, Pose A, Chomón B, Alvarez-Dobaño JM, Salgueiro M, Rodríguez Suárez JR. Diagnosis of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma. Chest. 1993 Feb;103(2):458–465 8. Sibley J C. A study of 200 cases of tuberculous pleurisy with effusion. Am Rev Tuberc 1950; 62:314-2 9. Basu A, Chakrabarti I, Ghosh N, Chakraborty S. A clinicopathological study of tuberculous pleural effusion in a tertiary care hospital. Ann Trop Med Public Health 2012;5:168-72 10. Ramyalakshmi KV et al. / Transworld Medical Journal. 2(2):94100. 11. Ray S , Mukherjee S , Ganguly J, Kumar A , Mitra S and Kundu S, A Cross-sectional Prospective Study of Pleural Effusion Among Cases of Chronic Kidney Disease. The Indian Journal of Chest Diseases & Allied Sciences;2013 (55): 210-213.Abstract
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