Title: Role of Antioxidants and Antioxidant Enzymes in Asthmatic Children
Authors: Neela A.Vaidya, P.M.Bulakh
DOI: http://dx.doi.org/10.18535/jmscr/v4i7.30
In children, respiratory system is not completely developed .Continuous exposure to environmental factors, pollutants and various infectious agents such as viruses, bacteria etc, makes the system vulnerable to inflammatory reactions. Epithelial cells, resident macrophages, endothelial cells and recruited inflammatory cells, generate ROS in response to increased levels of secretory toxins. ROS produced by phagocytes at sites of inflammation and increased oxidative stress are a major cause of cell and tissue damage associated with various acute and chronic inflammatory lung diseases. Clinically diagnosed and established seventy five cases of Asthma with sixty normal healthy controls in paediatric group were included in this study. 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