Title: Incidence and Clinical outcome of ovarian neoplastic tumors in pregnancy: A prospective case series and review of literature

Authors: Dr Priyanka Bhadana, M.B.B.S., M.S.(O&G),  Sumitra Bachani

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i7.27

Abstract

Objective: The purpose of this study was to review patients diagnosed with ovarian cancer in pregnancy and to assess their incidence, the effectiveness of the available methods of treatment and prognosis of these tumors.

Methods: A review of 11 women diagnosed to have cancer of the ovary associated with pregnancy who delivered at a tertiary care institute between Jan 2013 to Dec 2016. The clinical presentation, time and mode of diagnosis, treatment, pregnancy outcome and maternal survival were noted. The role and effect of surgery and chemotherapy on maternal and fetal outcome was noted.

Results: The incidence of ovarian carcinoma associated with pregnancy in this study was 0.265 per 1000 deliveries. Out of these women 63.6% (7/11) were primigravidas. 45.45% (5/11) women were asymptomatic at the time of presentation and diagnosed on routine ultrasonography. 7 patients had ovarian epithelial malignant neoplasia. Fetal survival rate was 81.81%.

Conclusions: Ovarian tumors in pregnancy are usually diagnosed early due to frequent routine examinations. Epithelial tumors constitute a majority of ovarian carcinomas. The surgical staging and management should follow the standard protocol, since outcome depends on the stage of lesion. Early diagnosis and prompt treatment offers the best prognosis for the patient

Keywords: Ovarian neoplasm; pregnancy; surgical staging; chemotherapy; tumour markers

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Corresponding Author

Dr Priyanka Bhadana, M.B.B.S.

Department of Obstetrics and Gynecology

Vardhman Mahavir Medical College and Safdarjung Hospital