Title: 105 Cases of Macrocytosis- Etiologic Profile Reflecting Lifestyle Changes

Authors: Dr M.C.Savithri, Dr K.P.Kavitha

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i7.20

Abstract

Macrocytosis is encountered frequently during medical practice. Megaloblastic anemia (MA) due to Vitamin B12 or folate deficiency is the well known cause of macrocytosis. Pernicious anemia is a major cause of megaloblastosis  in Western world where their diet supplies the necessary nutrients.[1]  Nutritional megaloblastic anemia is very important in the Indian scenario.[2]However non megaloblastic macrocytosis also forms an important group which includes  alcoholic liver disease, hemolytic anemias, leukemias etc. Kerala is a an Indian State where literacy rate is high. The rural urban divide is much less pronounced here and medical facilities are available even in the more remote areas. These lifestyle changes have influenced the disease spectrum of the state.

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Corresponding Author

Dr M.C.Savithri

Associate Professor, Dept of Pathology

Amala Institute of Medical Sciences, Thrissur, Kerala. India