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Category: Volume 4 Issue 07 July 2016
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Title: A Histopathological Study of Cholecystectomy Specimens

Author: Dr Dharmakanta Kumbhakar

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i7.10

Abstract

Background- Cholecystectomy specimen (gallbladder) is the most frequently encountered surgical specimen in a histopathology laboratory. It shows different histopathological changes ranging from inflammation to premalignant changes and carcinoma. Incidental detection of gallbladder cancer in cholecystectomy specimen has been reported in 0.3 to 2% of all cholecystectomies performed for benign condition.

Aims and objectives: To study the different histopathological entities of the cholecystectomy specimens and to find out the frequency of gallbladder cancer in these specimens.

Material and methods: The present study is based on histopathological analysis of 400 cholecystectomy specimens from June 1, 2014 to May 31, 2016 in the Department of Pathology, Tezpur Medical College and Hospital, Tezpur, Assam.

Results: Chronic cholecystitis (86.25%) was the most common finding in our study followed by cholesterolosis (7.50%) and various other mucosal pathologies of gallbladder. Female to male ratio was 4.71:1. Frequency of gallbladder cancer was 1.25%. The frequency of incidental carcinoma in the study was 0.75%. 

Conclusion: The study gives the different histopathological pattern of cholecystectomy specimens that attended our institute.  to reveal the different patterns of gallbladder lesions on histopathological examination. Thorough histopathological analysis of cholecystectomy specimens is important to detect incidental carcinoma.

Keywords: Gallbladder cancer, Cholecystectomy, Cholesterolosis, Xanthogranulomatous cholecystitis, Granulomatous cholecystitis, Adenocarcinoma.

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Corresponding Author

Dr Dharmakanta Kumbhakar

Associate Professor, Pathology Department, Tezpur Medical College and Hospital, Tezpur, Assam

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