Title: Histopathological Patterns of Ovarian Tumours: A Hospital Based Study
Author: Dr Dharmakanta Kumbhakar
DOI: http://dx.doi.org/10.18535/jmscr/v4i7.07
Background: - Ovary is the site for more than two dozens different tumours with its varied histopathological patterns. Relative frequency of these histopathological patterns is different for Western and Asian countries. Ovarian cancer is one of the most frequent causes of death from gynaecological malignancies. Aims and Objectives: - A hospital based study to determine the Histopathological pattern of the ovarian tumours. Material and Methods: - The present study is based on the histopathological analysis of 70 specimens of clinically and radiologically diagnosed ovarian tumours presented at Patholgy department of Tezpur Medical College and Hospital, Tezpur, Assam for histopatholcical examination in the period of two years from June 1, 2014 to May 31, 2016. Result and observations: - Out of 70 ovarian tumours, 46 (65.71%) were benign tumour, 2 (2.86%) were borderline and 22 (31.43%) were malignant tumour. Among benign tumours, benign cystic teratoma (30.00%) was the commonest followed by serous cystadenoma (22.86%) and mucinous cystadenoma (8.57%). Among the malignant tumours, the most common type was serous cystadenocarcinoma. Surface epithelial tumour (57.14%) was the commonest tumour according to the histogenesis followed by germ cell tumour (34.29%), sex cord tumours (7.14%) and metastatic tumour (1.43%). The mean age of the subjects was 35.2 years, ranging from 8 to 70 years. Abdominal mass was the most predominant clinical presentation. Conclusion:- Ovarian tumours need histopathological examination for proper diagnosis and follow up of patients. This study gives the histopathological pattern of ovarian tumours of the cases that attended our institute with different clinical presentations. As it is a hospital based study, it might not reflect the exact scenario of the population at large. Key Words: Surface epithelial tumour, Dermoid cyst, Cystadenocarcinoma Dysgerminoma, Sex cord stromal tumour, kruckenberg tumour. 1. Juan Rosai (2004), Rosai & Ackermann’s Surgical Pathology, 9th Edition. 2. Cotran, Kumar, Collins (2006), “The female genital tract” Robins Pathologic Basis of Disease. 3. Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumours and tumour-like lesions. Indian J Pathol Microbiol 2007; 50:525-7 4. Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histological pattern, Bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India. J Can Res Ther 2011; 7:433-7 5. Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer - the Indian scenario. Asian Pac J Cancer Prev 2009; 10:1025-30. 6. John D. Bancroft and Marilyn Gamble. Theory and Practice of Histological Techniques Couto F, Nadkarni NS, Jose M . Ovarian tumours in Goa. A Clinicopathological study. J Obstet Gynecol India 1993, 40 (20 408-11. 7. 7. Couto F, Nadkarni NS, Jose M . Ovarian tumours in Goa. A Clinicopathological study. J Obstet Gynecol India 1993, 40 (20 408-11. 8. Madan A, Tyagi SP, Mohsin S. Incidence of ovarian tumours in Aligarh with particular reference to histopathological typing. J Obsel Gynocol India, 1978; 827-32. 9. Verma K, Bhatia A, Ovarian neoplasm-A study of 403 tumours. J Obstel Gynocol India 1981, 406- 10. Prabarker, Maingi K. ovarian tumors – prevalence in Punjab. Indian J Pathol Microbiol 1989; 32: 276-81. 11. Mishra RK, Sharma SP, Gupta U, Gaur R, Mishra SD, Pattern of ovarin neoplasm in eastern UP. J Obstel Gynol, India 1992: 30:2420-46. 12. Pilli G, Sunita kp, Dhaded AV, Ovarian tumours, A study of 282 cases. JIMA. 2002; 100 (7): 1-6. 13. Bhuvanesh U and Logambal A, A study of ovarian tumours. J Osel Gyneacol INDIA 1978:28: 271-77Abstract
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