Successful Pregnancy Outcome in a Case of Dengue with Eclampsia

Title: Successful Pregnancy Outcome in a Case of Dengue with Eclampsia

Authors: Dr Poornima. M, Dr Preeti Lewis, Dr Vilas N Kurude, Dr Rekha G.Daver

DOI: http://dx.doi.org/10.18535/jmscr/v4i7.06

Abstract

Malaria and dengue are one of the commonest vector borne diseases seen in India. While management of uncomplicated dengue is usually symptomatic severe disease like dengue shock syndrome and dengue hemorrhagic fever may require tertiary medical care. Pregnancy complicated by dengue hemorrhagic fever is not usually seen in obstetric practice but with increase in cases of dengue in child bearing age group this incidence is expected to rise. Proper and in-time management of such cases are important as delay in treatment may adversely affect fetal and maternal well-being. Pregnancy complicated by dengue is also dangerous because it increases the risk of premature delivery, adverse neonatal outcome and post-partum hemorrhage. We here report a case of 3^rd gravida female with bad obstetric history who presented to us at 32 weeks of gestation with dengue hemorrhagic fever. This report emphasizes the complications of dengue infection in pregnancy. Early diagnosis, proper referral and immediate treatment are the key factors in the management of pregnancy complicated by dengue fever.

Key word: Pregnancy, Dengue, Thrombocytopenia, Post-partum hemorrhage.

References

1. Teoh BT, Sam SS, Tan KK, Johari J, Abd-Jamil J, Hooi PS, AbuBakar S. The Use of NS1 Rapid Diagnostic Test and qRT-PCR to Complement IgM ELISA for Improved Dengue Diagnosis from Single Specimen. Sci Rep. 2016 Jun 9;6:27663.

2. Chotigeat U, Kalayanrooj S, Nisalak A (2003) Vertical transmission of dengue infection in Thai infants: Two case reports. J Med Assoc Thai 86: 628-632.

3. Malhotra N, Chanana C, Kumar S (2006) Dengue infection in pregnancy. Int J GynaecolObstet 94: 131-132.

4. Salgado DM, Rodríguez JA, Lozano Ldel P, Zabaleta TE. [Perinatal dengue].Biomedica. 2013 Sep;33Suppl 1:14-21. Review. Spanish. PubMed PMID: 24652245.

5. Friedman EE, Dallah F, Harville EW, et al. Symptomatic Dengue Infection during Pregnancy and Infant Outcomes: A Retrospective Cohort Study. Lopes da Fonseca BA, ed. PLoS Neglected Tropical Diseases. 2014;8(10):e3226. doi:10.1371/journal.pntd.0003226.

6. Teeraratkul A, Limpakarnjanaral K. Three decades of dengue hemorrhagic fever surveillance in Thailand 1958–1987. Southeast Asian J Trop Med Public Health. 1990;21:684.

7. Malavige GN, Velathanthiri VG, Wijewickrama ES, Fernando S, Jayaratne SD, Aaskov J, Seneviratne SL (2006) Patterns of disease among adults hospitalized with dengue infections. QJM 99: 299-305.

8. Atypical lymphocyte in dengue hemorrhagic fever: its value in diagnosis. Thisyakorn U, Nimmannitya S, Ningsanond V, Soogarun S Southeast Asian J Trop Med Public Health. 1984 Mar; 15(1):32-6.

9. Kassim FM, Izati MN, TgRogayah TA, Apandi YM, Saat Z. Use of dengue NS1 antigen for early diagnosis of dengue virus infection. Southeast Asian J Trop Med Public Health. 2011 May;42(3):562-9. PubMed PMID: 21706934.

10. Chye JK, Lim CT, Ng KB, Lim JM, George R, Lam SK. Vertical transmission of dengue. Clin Infect Dis. 1997;25:1374–1377.

Corresponding Author

Dr Poornima M

Resident, Department of Obstetrics and Gynecology,

Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai