Title: Outcome of Patients with Acute Aluminium Phosphide Poisoning In a Tertiary Care Hospital of Haryana
Author: Dr Rajpal Verma
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.48
Background: The only factor that determines the severity and monitors the progress of cases of AIP poisoning is blood phosphine level. The mortality is highly variable depending on the freshness and dose of the compound consumed. The present study has been designed to determine the serial levels of phosphine in blood and to correlate them with outcome of the patients. Materials: Fourty five patients of aluminium phosphide poisoning irrespective of age, sex, dose and duration, admitted in Medical College, Rohtak were studied. The patients were grouped in I,II, IIa, IIb. Data was collected on a semi structured schedule and consent was taken. Appropriate staistical tests were applied. Observations: The blood phosphine levels at admission, at 12 hours and 24 hours in group-I patients were significantly higher than patients of group-II A & B, making the conclusion that group-I patients had severe intoxication and consumed active and fresh compound. In group-II A patients, blood phosphine levels at admission, at 12 hours and 24 hours were significantly lower than group-I but higher than group-II B paitents. This indicated that compound consumed by group-II A patients was still active but less than group-I. These patients had mild intoxication. 1. Chugh SN, Sant Ram, Chugh K, Malhotra KC. Spot diagnosis of aluminium phosphide ingestion – an Application of a simple test. AAssor Physician Ind 1989: 37: 219-220. 2. Chugh SN, Dushyant, Sant Ram, Arora B, Malhotra KC Incidence and outcome of aluminium phosphide poisoning in a hospital study. Ind J Med Res 1991: 94: 232-35. 3. Chugh SN, Arora V, Sharma Chugh K, free redical scavenging enzymes in acute aluminium phosphide poisoning. Md thesis 1993 Maharishi Dayanand University, Rohtak, Haryana (India). 4. Katira R, Elkhence GP, Malhotra ML et al. A study of aluminium phosphide poisoning with electrocardiographic change. J Assor physicians Indi 1990; 38: 471-74 5. Chugh SN, Mittle A, Seth S, Chugh K. Lipid peroxidation and lipid metabolism in acute aluminium phosphide poisoning . MD thesis 1992 MaharshiDayanand University, Rohtak, Haryana (India). 6. Jain SM, Babarani A, Sepatha GS, Sanghi VC, Raman PG. Electrocardiographic changes in aluminium phosphide poisoing. J Assoc Physicians Ind 1985; 33: 406-9. 7. Siwach SB, YadavDr, Arora BB, Dalal S, Jagdish. Acute AIP poisoning – An epidemiological, clinical and histopat-hological study. J Assoc PhusicianInd 1988; 36; 594-596. 8. Chugh SN. Aluminium phosphide poisoning – present status and management. It Assoc physicians Ind 1992; 40: 401-494. 9. Raman R, Dubey M. The electrocard-iographic change in Quickphos poisoning. Indian Heart J 1985; 37: 193.Abstract
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