Title: Profile of Patients with Acute Aluminuim Phosphide Poisoning in a Tertiary Care Institute of Haryana
Author: Dr Rajpal Verma
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.44
Background: The Pesticides have proved to be a boon to the farming community to save the grains from pests and rodents etc. Aluminium phosphide (AIP), a solid fumigant pesticide is widely used as a grain preservative in Northern India. The mode of poisoning is usually intentional, occasionally accidental and rarely homicidal. The agriculture community is more at risk due to illiteracy and easy availability of the pesticide in the house hold. Materials: Fourty five patients of aluminium phosphide poisoning irrespective of age, sex, dose and duration, admitted in Medical College, Rohtak were studied. The patients were grouped in I, II, IIa, IIb. Data was collected on a semi structured schedule and consent was taken. Appropriate staistical tests were applied. Observations: The poisoning was more common in younger age group. 22 (73%) patients out of 30 in group-I and 14 (93%) patients out of 15 in group-II fell in age group between 14-30 years. The poisoning was more common in males than in females. Male to female ratio was 2:1. The earliest symptoms and signs pertain to gastrointestinal tract followed by cardiovascular system. 1. Chugh SN, Dushyant, Sant Ram, Arora B, Malhotra KC Incidence and outcome of aluminium phosphide poisoning in a hospital study. Ind J Med Res 1991: 94: 232-35. 2. Thomas PM. Aluminimum phosphide and ideal fumigant. Pesticide 1973; XII (B): 15-16. 3. Siwach SB, Yadav Dr, Arora BB, Dalal S, Jagdish. Acute AIP poisoning – An epidemiological, clinical and histopathological study. J Assoc Phusician Ind 1988; 36; 594-596. 4. Jain SM, Babarani A, Sepatha GS, Sanghi VC, Raman PG. Electrocardiographic changes in aluminium phosphide poisoing. J Assoc Physicians Ind 1985; 33: 406-9. 5. Chugh SN, Sant Ram, Chugh K, Malhotra KC. Spot diagnosis of aluminium phosphide ingestion – an Application of a simple test. A Assor Physician Ind 1989: 37: 219-220. 6. W.H.O. Phosphine and selected Metal Phosphine (Environement Health Grieteria -73) Geneva 1988: pp 80-83. 7. Houston MC, Thompson W, Robertson Q. Shock diagnosis and management. Arch Intern Med 1984; 144: 1433-39. 8. Netelson S. Blood urea notrogen. In micro technique of clinical chemistry for routine laboratory. CC Thomas (ed) Springfield, IIIinois 1957; pp 30. 9. Dubowskie KM. An orthotoludine method for body fluid glucose determinations. Clin Chem 1962; 8: 215. 10. Varley H. Estimation of serum creatinine and creative. In: Practical clinical chemistry. New York: Interscience (Pub) Inc 1967; PP 197-200. 11. Evelyn KA, Malloy HT. Estimation of serum bilirubin. J Bio Chem 1937; 119: 481. 12. Retimane, Frankel S. Estimation of SGOT/SGPT. Am J Clin Path 1957; 28: 56. 13. King RPN, Kin EJ. Estimation of alkaline phosphatase. J Clin Pathol 1954; 7: 322. 14. Chugh SN. Aluminium phosphide poiso-ning – present status and management. It Assoc physicians Ind 1992; 40: 401-494. 15. Singh S, Dilawari JB, Vashisht R, Malhotraj HS, Sharma BK. Aluminimum phosphide ingestion. Br Med J 1985; 290: 1110. 16. Sarswat PK, Gupta BP, Malhotra VK, Goyal VK. Prevelence of fatalities due to aluminium phosphide ingestion in Southern Rajashtan (An epidemiological study). J Forens Med Toxicol 1986; 11: 1 17. Chugh SN, Singhal HR, Girdhar NK, Arora B, Malhotra KC. AIP poisoning; analysis of 228 cases. J Assoc Physicians India 1989; 37:28. 18. Wayland J, Hayes Jr. Pesticide Study in man. Baltimore, London: William and Wilkins Pub 1982; 7: 133-135. 19. Raman R, Dubey M. The electrocardiographic change in Quickphos poisoning. Indian Heart J 1985; 37: 193. 20. Chugh SN, Mittle A, Seth S, Chugh K. Lipid peroxidation and lipid metabolism in acute aluminium phosphide poisoning . MD thesis 1992 Maharshi Dayanand University, Rohtak, Haryana (India).Abstract
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