Title: Screening of Preterm Infants for Retinopathy of Prematurity

Authors: Dr Basant Saraswat, Dr M Nikhila C Jain, Dr (Prof).Vijay Bhaisare, Dr Neetu Kori, Dr Preeti Rawat, Dr ShwetaWalia, Dr Parul Verma

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i8.79

Abstract

Introduction -To find the incidence of ROP in preterm and LBW infants and to evaluate various risk factors

Discussion- Retinopathy of prematurity is a disorder of the developing retinal blood vessels of the premature infant and is a complex disease ranging from mild transient changes to severe vasoproliferation, scarring and detachment leading to blindness

Methodology –In this study, sample population of 232 preterm babies from special neonatal care unit of our hospital from September 2014 – August  2015.Babies with Low birth weight, oxygen exposure, septicaemia, anemia, phototherapy, Jaundice ,RDS, Blood transfusion and hyperbilirubinaemia were included

Conclusion­- In our study, the overall incidence of ROP was 18.53% .Regression rate was 79.06 % which is in concordance with literature. Although significant advances have been made in perinatal care, ROP remains a serious complication in premature babies.

Key words-Retinpathy of  prematurity, preterm,  risk factors

References

 

1.      Terry TL. Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens. Am J Opthalmol. 1942;25:203–6.

2.      Valentine PH, Jackson JC, Kalina RE, Woodrum DE. Increased survival of low birth weight infants: Impact on the incide-nce of retinopathy of prematurity.  Pedia-trics.1989;84:442–5. [PubMed: 2788864]

3.      Deborah KV, John AF. Retinopathy of prematurity. In: Cloherty JP, Eichenwald EC, Stark AR, editors. Manual of Neonatal Care. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2004. pp. 640–4.

4.      Rekha S, Battu RR. Retinopathy of prematurity: Incidence and risk factors. Indian Pediatr. 1996;33:999–1003. [PubMed: 9141799]

5.      Charan R, Dogra MR, Gupta A, Narang A. The incidence of retinopathy of premat-urity in a neonatal care unit. Indian J Ophthalmol. 1995;43:123–6.[PubMed: 8822486]

6.      Kim TI, Sohn J, Pi SY, Yoon YH. Postnatal risk factors of retinopathy of prematurity. Paediatr Perinat Epidemiol.  2004;18:130–4. [PubMed: 14996252]

7.      Kaempf JW, Kaempf AJ, Wu Y, Stawarz M, Niemeyer J, Grunkemeier G. Hyperglycemia, insulin and slower growth velocity may increase the risk of retinopathy of prematurity. J Perinatol.  2011;31:251–7. [PubMed: 21233796]

8.      Cooke RW, Clark D, Hickey-Dwyer M, Weindling AM. The apparent role of blood transfusions in the development of retinopathy of prematurity. Eur J Pediatr. 1993;152:833–6. [PubMed: 8223786]

9.      Gupta VP, Dhaliwal U, Sharma R, Gupta P, Rohatgi J. Retinopathy of prematurity - risk factors. Indian J Pediatr. 2004;71:887–92. [PubMed: 15531829]

10.  Chinese Medical Association. Guidelines on oxygenation policies and on prevention and treatment of retinopathy of prematurity.  Zhonghua Yan KeZa Zhi.2005;41:375–6.

11.  American Academy of Pediatrics Section on Ophthalmology; American Academy of Ophthalmology; American Association for Pediatric Ophthalmology and Strabismus. Screening examination of premature infants for retinopathy of prematurity.  Pediatr. 2006;117:572–6.

12.  KumarP, SankarMJ,DeorariA,et al. Risk factors for severe retinopathy of prematurity in preterm low birth weight neonates Indian J Pediatr 2011;78:812--6.

13.  Murthy KR, Nagendra BK. Analysis of risk factors for the development of ROP in preterm infants at a tertiary referral hospital in South India. ActaMedica Lituanica.2006;13:147–51

14.  Lancet Ann Hellström, Lois E H Smith, Olaf Dammann. Retinopathy of prematurity. Lancet 2013; 382: 1445–57

15.  Palmer AE, Hardy RJ, Dobson V. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Outcomes following Threshold Retinopathy of Prematurity. Final results from the multicenter trial of cryotherapy for retin-opathy of prematurity. Arch Ophthalm-ol. 2005;123:311–8. [PubMed: 15767472]

16.  Early Treatment For Retinopathy Of Prematurity CooperativeGroup. Revised indications for the treatment of retinopathy ofprematurity: results of the early treatment for retinopathy of prematurity randomized trial. Arch Ophthalmol2003; 121:1684–94.

17.  Coats DK, Aaron MM, Mohamed AH. Involution of retinopathy of prematurity after laser treatment:     Factors associated with development of retinal detachment.  Am J Ophthalmol.  2005;140:214– 22. [PubMed: 16086945]

Corresponding Author

Dr M Nikhila C Jain

Address-Flat no-404, Geetanjali Apartments, Indore-452001

Email-This email address is being protected from spambots. You need JavaScript enabled to view it., Phone-7869263366