Title: Metstatic and Mortality Pattern in Carcinoma of Breast Patients in Tertiary Health Care Centre
Authors: Neelesh Shrivastava, Dr Rachana Gupta, Dr A.P.S Gaharwar, Dr Yogesh Kailasiya
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.78
Introduction: carcinoma breast is second common cancer after Carcinoma cervix in India. Globally, it accounts for 25% of female cancers and 18% of death from cancer in women1. Previous studies were shows high incidence of breast cancer and cancer related mortality among post menopausal females in India. This study to find out metastatic and mortality pattern in breast cancer patient which was not carried out in this part of country. Material and methods: this is a prospective analysis (2013-2014) of database from all surgical units of S.S. Medical College, Rewa, India. Result: The incidence of carcinoma of breast was 25.83%, amongst the total admitted cancer patients. Peak incidence 31.4% was in the age range 41-50 years, with the mean age of 45.2 years. All patients were females and (98.5%) were married. 67.1% patients were from rural area and 32.8% were from urban area. most of the patients were illiterate 50(71.4%) while 20(28.5%) patients were literate. Out of 70 patients, 12 patients had metastatic lesion. Secondary’s in lung account for 75% of metastatic lesion and 12.8%of total ca breast patients followed by secondary’s in liver account for 33.3% of metastatic lesion and 5.7% of total ca breast patients. Lymph oedema of arm was 16.6% of metastatic lesion and 2.8% of total ca breast patients. Skeletal metastasis was present only in one patient. Mortality was 5.71%.i.e 4 patients of carcinoma of breast who present in stage IV and were having malignant pleural effusion and/ or multiple liver metastasis and/ or lymph oedema of arm. Conclusion: It is concluded from this study that factors associated with increase in mortality were old age, female gender, and illiteracy, and marital status, presence of distant metastasis and late stage of disease. For reducing the mortality due to breast cancer early screening and proper education to high risk and unaware population is needed. Keywords: Breast carcinoma, Mortality, Female, Metastasis. 1. MN Okobia and U Osime. Clinicopatho-logical study of Carcinoma of the Breast in Benin City. Dept of Surgery, College of Medical Science, University of Benin Teaching Hospitals Benin City Nigeria. African Journal of Reproductive Health. page 57-62. 2. Samina Khokher, Muhammad Usman Qureshi, Masooma Riaz, Naseem Akhtar, Afaf Saleem, Clinicopathologic Profile of Breast Cancer Patients in Pakistan: Ten Years Data of a Local Cancer Hospital, (2012) 3. Hafiz Muhammad Aslam; clinico-pathological profile of patients with breast disease, Aslam et al, diagnostic pathology 2012. 4. B. Mcn. Truscott. Carcinoma of The Breast. An Analysis OfThe Symptoms, Factors Affecting Prognosis, Results Of Treatment And Recurrences In 1211 Cases Treated At The Middlesex Hospital.From the Middlesex Hospital, London, W.I. Received for publication March 25, 1947. 5. W. L. Harnett., Statistical Report On 2529 Cases Of Cancerof The Breast.Published for the Clinical Cancer Research Commi-ttee ofthe British Empire Cancer Campai-gn. Received for publication July 16, 1948 6. Kaushik Saha, Gargi Raychaudhuri, Bitan Kumar Chattopadhyay. Clinico-patholo-gical study of breast carcinoma: A prospe-ctive two year study in a tertiary care hospital. Clinical Cancer Investigation Journal 2013;2(1):34-40. 7. N.A.S. Alwan, breast cancer, demographic characteristic and clinic pathological presentation of patients in Iraq, EMHJ VOL.16,2010. 8. L.M.D. Yusufu,V.I.Odigie and A Moham-mad, Breast Mass In Zaria, Nigeria, Annals of African medicine ,vol.2,2003Abstract
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