Title: A Rare Case of Cerebral Infarction in a Young Female Following Snake Bite
Authors: Dr Maitrey Patel, Dr Basavraj R Patil Raikood
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.41
Ischemic stroke following snake bite is rare. We report a 35 year female developed right sided hemiplegia with left UMN facial palsy with broca’s aphasia following a snake bite.CT brain plain showed acute large infarct in left middle cerebral artery territory. The possible mechanisms for cerebral infarction in this scenario include disseminated intravascular coagulation, toxin induced vasculitis and endothelial damage. 1. Kasturiratne A, Wickramsinghe AR, Desilva N, et al. The global burden of snakebite: A literature analysis and modelling based on regional estimates of envenoming and deaths. PLOS Med. 2008; 5:e218. 2. Simpson ID, Norris RL. Snakes of medical importance In India: is the concept of big four still relevant and Useful? Wilderness and environmental medicine2007;18(1):2-9. 3. Mosquera A, Idrovo LA, Tafur A, Del Brutto OH.Stroke following bothrops spp. Snakebite. Neurology 2003; 60(10):1577-80. 4. Simpson ID. Snakebite management in India, the first few hours: a guide for primary care physicians. J Indian med assoc. 2007; 105:324- 35. 5. Farid TM, TU at, el-Asmar MF. Effect of cerastobin, a thrombin like enzyme from cerastes viper (Egyptian Sand snake) venom, on human platelets. Haemostasis 1990; 20(5):296-304. 6. Basheer AR, el-Asmar MF, Soslau G. Characterization of a potent platelet aggregation inducer from cerastescerastes (Egyptian sand viper) venom. Biochimbi-ophysacta 1995 jul 3;1250(1):97-109. 7. Dekhil H, Wasner A, Marrakchi N, Ayed M, Bon C,Karoui H. Molecular cloning and expression of a Functional snake venom serine proteinase, with platelet Aggregating activity, from cerastes viper. Biochemistry 2003 sep16;42(36):10609-18 8. Marrakchi N, Barbouche R, Guermazi S, Bon C, el-Ayeb M. Procoagulant and platelet aggregating Properties of cerastocytin from Cerastescerastesvenom. Toxicon 1997 Feb; 35(2):261- 72. 9. Marrakchi N, Barbouche R, Guermazi S, Karoui H,Bon C, El-Ayeb M. Cerastotin, a serine protease from Cerastescerastes venom, with platelet-aggregating and Agglutinating properties. Eur j biochem. 1997 Jul 1; 247(1):121-8. 10. Laraba-Dejabri F, Martin-Eauclaire MF, Mauco G, Marchot P. Afaacytin, an alpha beta-fibrinogenaseFrom cerastescerastes(horned viper) venom, activates Purified factor x and induces serotonin release from Human blood platelets. Eur j biochem 1995 Nov 1; 233(3):756-65 11. Soslau G, el-Asmar MF, Parker j. Cerastescerastes(Egyptian sand viper) venom induced platelet aggregation as compared to other agonist Biochem-biophys res commun 1988;150:909-916. 12. Ariaratnam A, Sjostrom L, Raziek Z, et al. An open Randomized trial of two antivenoms for the treatment of envenoming by Sri Lankan Russel’s viper. Trans R soc trop med hyg 2001; 95:74-80. 13. Bashir R, Jinkins J. Cerebral infarction in a young Female following snake bite. Stroke 1985; 16:328-30. 14. Torvik A.the pathogenesis of watershed infarcts in the brain. Stroke1984; 15:221-3.Abstract
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