Title: Spectrum of CT Angiographic Findings in a Series of 114 Patients of Clinically Suspected Cases of Takayasu Arteritis – A Prospective Study at a Teritiary Care Hospital in India
Authors: Dr Shanthi Sree .V, Dr Hanumath Prasad.V, Dr Anil Kumar, Dr Shivani, Dr Veena
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.37
Aims & Objectives: 1) To detect various angiographic patterns by CT angiography in clinically suspected 114 cases of Takayasu’s arteritis.2)To characterize & classify the lesions into various subgroups 3) To evaluate diagnostic & clinical usefulness of CT angiographic cross sectional imaging for establishing the diagnosis of Takayasu’s Arteritis 4) To discuss the differential diagnosis. Summary: In our study group, the age of clinical onset of disease varied from 7 yrs to 50 yrs with female preponderance. The commonest site of involvement in our study is Abdominal aorta & the second common site was Renal artery. The younger age group of patients showed more extensive involvement & in multiple vessels Keywords: Takayasu’s arteritis, CT angiography. 1. F.P Zhu ,MD ,S Luo ,MS and G.M Lu,MD-Takayasu arteritis : Imaging spectrum at Multidetector CT angiography .British journal of radiology 2012 Dec;85 ( 1020 ):e 1282- e 1292 2. Hata A , Noda M , Moriwaki R , Numana F : Angiographic findings of Takayasu arteritis new classification .Int.J Cardiool 1996 : 54 suppl: 5155-63 3. Khandelwal N ,Kalra N , Garg MK , Kang M , Lal A ,Jan S et al Multidetector ct angiography in Takayasu arteritis .Eur. J . Radiol 2011 ;77:369-74 4. Weynad CM , Goronzy JJ Medium and Large vessel vasculitis N. Eng.I.Med 2003 ;349:160- 9 5. Mnif N , Chaker M , Oueslati S ,Tenzakhti F ,Turki S et al Abdominal polyarteritis Nodosa angiographic features J.Radiol 2004 ;85:635- 8 6. Matsunga N ,Hayashii K, Sakamoto J, Ogawa Y, Matsumoto J Takayasu arteritis protean radiologic manifestations and dia-gnosis .Radiographics 1997;17: 579-594 7. Michael B Gotway .Philip A Araoz ,Thanila A Macedo ,A NTHONY we Statson ,Charles B Higgins ,Earnest J Ring ,Samuel K Daon ,W Richard Webb ,Jessica W T Leung and Gautham P Reddy Imaging findings in Takasu arteritis AJR Vol 184 June 2005 Issue 6 ,Pg 1945- 1950 8. Linu Cherian Kuruvilla ,Correlation of Computed tomography angiography and digital substraction angiography in nonsp-ecific aortoarteritis (Takayasu arteritis) medical journal of DY Patil University, vol 9 no :2 ,March-April 2016 ,pp 209-215 9. Kerr GS, Hallahan CW, Giordano J, et al. Takayasu arteritis. Ann Intern Med 1994; 120:919–29. 10. Ishikawa K. Natural history and classific-ation of occlusive thromboaortop-athy (Takayasu's disease). Circulatio-n 1978;57:27–35. 11. S.L Johnston , R J Lock and M M Gompels Takayasu arteritis : a review J Clin pathol ,2002 jul : 55 ( 7 ): 481 -486 12. Salazar M, Varela A, Ramirez LA, et al. Association of HLA-DRB1*1602 and DRB1*1001 with Takayasu arteritis in Colombian mestizos as markers of Amerindian ancestry. Int J Cardiol 2000; 75:S113–16. 13. Vargas-Alarcón G, Zúñiga J, Gamboa R, et al. DNA sequencing of HLA-B alleles in Mexican patients with Takayasu arteritis. Int J Cardiol 2000;75:S117–22. 14. Khraishi MM, Gladman DD, Dagenais P, et al. HLA antigens in North American patients with Takayasu arteritis. Arthritis Rheum 1992;35:573–5. 15. Cong XL, Dai SM, Feng X, Wang ZW, Lu QS, Yuan LX, et al. Takayasu's arteritis: clinical features and outcomes of 125 patients in China. Clin Rheumatol 2010; 29:973–81.Abstract
Conclusion: CT angiography is one the most reliable ,relatively commonly available method of investigating Takayasu arteritis as it can provide reliable information regarding the mural & luminal abnormalities of aorta & its branches & pulmonary artery References