Title: A Retrospective Cytological Study of All Solitary Thyroid Nodules
Authors: Sudha Iyenger, Shruti Gupta, Dharmesh Chandra Sharma, Sunita Rai, Rajesh Gaur
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.27
Background- Fine Needle Aspiration Cytology (FNAC) is widely considered as diagnostic study of choice in assessment of thyroid lesions. Aim- The aim of this study is to determine the various cytological patterns found in all Solitary thyroid nodules (STNs). Setting and Design- The present study is a five retrospective study of FNAC of thyroid STNs performed in pathology department of our institute during the period of January 2009 to December 2013. Material and Methods- The records of 185 patients who had undergone FNAC during the study period were retrieved and information about age, sex and cytological diagnosis were extracted and the corresponding original slides were reviewed. Cytological diagnosis were categorized as Neoplastic (benign/malignant), Non-neoplastic (nodular colloid goiter, colloid cyst, thyroiditis) and third category as suspicious (follicular neoplasm). Results:- A total of 185 FNACs of STNs were done during the study period. The results of cytological diagnosis showed that 11 cases (5.94%) had neoplastic cytological pictures (benign/malignant), 140 cases (73.37%) had non-neoplastic pictures of STN. The cytological picture also showed 37 cases (19.69%) were suspicious cytomorphology. Conclusion- FNAC is a sensitive, specific and accurate initial diagnostic test for preoperative evaluation of STN and can be easily performed as an OPD procedure. Keywords: Fine needle aspiration cytology, solitary thyroid nodule. 1. H. Thyroid: Fine Needle Aspiration (FNA) and Cytology. Thyroid 2003;13:80-6. 2. Galera – Davidson H. Diagnostic problems in thyroid fine needle aspirations. Diag cytopathology 1997, 1:194-202. 3. Reeve D, Delbridge L, Sloan D, Crummer P. The impact of fine needle biopsy in surgery for single thyroid nodule. Med J Aust 1986, 145:308-311. 4. Ogilvie JB, Piatgorsky EJ, Clark OH. Current status of fine needle aspiration for thyroid nodules. Adv surg rev 2006;40: 233-38. 5. Gharib H. Fine needle aspiration biopsy of thyroid nodules: Advantages, limitations and effects. Mayo Clin Proc 1994;79:335-9. 6. Fon LJ, Deans GT, Lioe TF et al. An audit of thyroid surgery in a general surgical unit. Ann R Coll Surg Eng 1996,78:192-196. 7. Bukhari MH, Niazi S, Hanif G, Qureshi SS, Munir M, et al. An updated audit of fine needle aspiration cytology procedure of solitary thyroid nodule.Diagn Cytopathol 2008; 36:104-12. 8. Borget I, Vielh P, Leboulleux S, Allyn M, Iacobelli S, Schlumberger M, et al.Assessment of cost of fine needle aspiration cytology as a diagnostic tool in patients with thyroid nodules. Am J Clin Pathol 2008;129:763-71. 9. Shaha AR. Controversies in the management of thyroid nodule. Laryngoscope 2000; 110:183-93.Abstract
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