Title: Clinical Implication of Lactate Monitoring in Intensive Care Unit: An Observational Study

Authors: Dr Nisha, Dr Uday.G, Dr B.Khanam

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i9.22

Abstract

Introduction: Lactate is common parameter in critically ill patients. It is mainly used to diagnose inadequate tissue oxygenation; other processes are not related to tissue oxygenation may increase lactate level. In critically ill patients increase glycolysis may be an important cause of hyperlactemia. The presence of increase lactate has significant implication for morbidity and mortality. Lactate play important role in early resuscitation. lactate can be measure bedside rapidly.

Aim: 1) To study the significance of lactate level in critically ill patients.2) to study the role of lactate in early resuscitation.

Material and Methods: It is a simple random sampling study of 100 patients admitted to intensive care unit of index hospital from 2014 to 2015. Patients lactate level are studied by arterial blood gas analysis and their correlation with spo2;PH and Pao2 and PaCO2 and glucose  is studied.

Result: lactate level are increased in critically ill patients and it is related to tissue hypoxia and it leads to significant morbidity and mortality.

Conclusion: lactate level may be an epiphenomena of severity of disease .clinician can interpret hyperlactemia as warning signal that patients are deteroiting in spite of stable hemodynamic parameters and take as early marker of resuscitatory measure.

Keywords: lactate, intensive care unit, resuscitation, prognosis.

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Corresponding Author

Dr Nisha

Dept of Internal Medicine

Index Medical College and Research Center, Indore, Madhya Pradesh, India

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