Title: Study of Emergency Intestinal Resection and Anastomosis in Adults

Authors: Dr Aarti Mitra, Dr Unmed Chandak, Dr Ninad Sawant, Dr Rachit Mitra

 DOI:  https://dx.doi.org/10.18535/jmscr/v4i10.118

Abstract

Aims and Objectives: (1) To study the emergency intestinal resection and anastomosis. (2) To study various intestinal pathologies for which emergency intestinal resection and anastomosis was performed. (3)To study various complications associated with emergency intestinal resection and anastomosis (4) To study the morbidity and mortality associated with emergency intestinal resection and anastomosis (5) To study various risk factors responsible for failure of emergency intestinal resection and anastomosis

Study Design: It was prospective study done over a period of 2 years conducted at a tertiary care hospital. All patients admitted to any surgical unit in our institute aged between 18-80 years in whom emergency intestinal resection and anastomosis was performed were enrolled in this study.

Materials and Methods: The study was approved by the Institutional ethical committee. The patients admitted in any surgical unit and fulfilling the criteria were enrolled in the study. After detailed history and detailed investigations the etiopathology, risk factors, complications, morbidity and mortaility patterns were studied in the patients who have undergone emergency resection and anastomosis. Failure of anastomosis along with risk factors were also studied.

Results: Amongst the studied cases 62 (67.4% ) were females and 30 (32.6%) were males with an overall mean age of Mean age of 41.34 years. The minimum duration of complaints was 2 days while maximum duration of complaints was 15 days with a mean duration being 4.27 days. Most of the patients were anaemic and only one patient had Hb of more than 12 gm%.22 (23.91%) patients had Sr albumin levels less than 3.5 gm %. Most common co-morbid conditions seen in patients was diabetes and hypertension which was seen in 7 (7.6 %) patients. 72 patients had no co-morbidities. 44 (47.82%) patient had evidence of some contamination either in the form of infected free fluid, pus , focal matter or combination of above. 19 (20.65%) patients required some kind of inotropic support either before, during or after surgery. Out of the studied cases 48 (52.17%) patients required blood or blood product transfusion. The most common pathologies for which emergency resection and anastomosis was done were stricture in small bowel and malignancy in large bowel. Most common anastomosis done was ileo-ileal which was done in 42 patients. Ileo-descending and jejuno-ascending were done least frequently ie in 1 patient each. Drainage of peritoneal cavity was done in 78 (84.78%) patients. The most common complications seen in the patients were wound infection and fever which were seen in 58 (63.04%) and 42 (45.65%) patients respectively. The mean duration of hospital stay was found to be 12.70 days and death occurred in 11(11.92%) patients.

Conclusion: This study summarizes the main pathologies, risk factors, complications, morbidity and mortality rates and outcome in patients who have undergone emergency resection and anastomosis at a tertiary care hospital. In order to reduce complications it is important to know these risk factors and complication so that strategies to prevent, treat or reduce these complications can be made.

Keywords: Emergency resection and anastomosis, risk factors, complications.

References

1.      Herrington JL, Lawler M, Thomas TV, Graves HA. Colon resection with primary anastomosis performed as an emergency and as a non-planned operation. Annals of Surgery. 1967;165(5):709-720.

2.      Kirchhoff P, Clavien P-A, Hahnloser D. Complications in colorectal surgery: risk factors and preventive strategies. Patient Safety in Surgery. 2010;4:5.

3.      Dindo D, Demartines N, Clavien P-A. Classification of Surgical Complications: A New Proposal With Evaluation in a Cohort of 6336 Patients and Results of a Survey. Annals of Surgery. 2004;240(2):205-213.

4.      Artinyan A, Nunoo-Mensah JW, Balasubramaniam S, Gauderman J, Essani R, Gonzalez-Ruiz C, Kaiser AM, Beart RW Jr. Prolonged postoperative ileus-definition, risk factors, and predictors after surgery. World J Surg. 2008;32:1495–1500.

5.      Shaffer VO, Baptiste CD, Liu Y, et al. Improving Quality of Surgical Care and Outcomes: Factors Impacting Surgical Site Infection after Colorectal Resection. The American surgeon. 2014;80(8):759-763.

6.      Hyman N, Manchester TL, Osler T, Burns B, Cataldo PA. Anastomotic Leaks After Intestinal Anastomosis: It’s Later Than You Think. Annals of Surgery. 2007;245(2):254-258.

7.      Binda GA, Karas JR, Serventi A, Sokmen S, Amato A, Hydo L, Bergamaschi R; Study Group on Diverticulitis.. Primary anastomosis vsnonrestorative resection for perforated diverticulitis with peritonitis: a prematurely terminated randomized controlled trial. Colorectal Dis. 2012 Nov;14(11):1403-10.

8.      Turrentine FE, Wang H, Simpson VB, Jones RS.Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg. 2006 Dec;203(6):865-77.

9.      Krell RW, Girotti ME, Dimick JB. Extended length of stay after surgery: complications, inefficient practice, or sick patients? JAMA Surg. 2014 Aug;149(8) :815-20.

10.  Lipska MA, Bissett IP, Parry BR, Merrie AE. Anastomotic leakage after lower gastrointestinal anastomosis: men are at a higher risk. ANZ J Surg. 2006 Jul;76(7):579-85.

11.  Vallicelli C, Coccolini F, Catena F, et al. Small bowel emergency surgery: literature’s review. World Journal of Emergency Surgery: WJES. 2011;6:1.

12.  Sawai RS. Management of Colonic Obstruction: A Review. Clinics in Colon and Rectal Surgery. 2012;25(4):200-203.

13.  Ruggiero R, Sparavigna L, Docimo G, Gubitosi A, Agresti M, Procaccini E,Docimo L. Post-operative peritonitis due to anastomotic dehiscence after colonic resection. Multicentric experience, retrospective analysis of risk factors and review of the literature.AnnItalChir. 2011 Sep-Oct;82(5):369-75.

14.  Chen K-N. Managing complications I: leaks, strictures, emptying, reflux, chylothorax. Journal of Thoracic Disease. 2014;6(Suppl 3):S355-S363.

15.  Tartter PI. The association of perioperative blood transfusion with colorectal cancer recurrence. Annals of Surgery. 1992;216(6):633-638.

16.  Edna TH, Bjerkeset T. Perioperative blood transfusions reduce long-term survival following surgery for colorectal cancer. Dis Colon Rectum. 1998 Apr;41(4):451-9.

17.  Aquina CT, Blumberg N, Probst CP, Becerra AZ, Hensley BJ, Noyes K, Monson JR,  Fleming FJ. Large Variation in Blood Transfusion Use After Colorectal Resection: A Call to Action. Dis Colon Rectum. 2016 May;59(5):411-8.

18.  Van Laarhoven CJHM, Andriesse GI, Schipper MEI, Akkermans LMA, van Vroonhoven TJMV, Gooszen HG. Ileoneorectal Anastomosis:  Early Clinical Results of a Restorative Procedure for Ulcerative Colitis and Familial Adenomatous Polyposis Without Formation of an Ileoanal Pouch. Annals of Surgery. 1999;230(6):750.

19.  Calin M, Bălălău C, Popa F, Voiculescu S, Scăunașu R. Colic anastomotic leakage risk factors. Journal of Medicine and Life. 2013;6(4):420-423.

20.  Iesalnieks I, Kilger A, Glass H, Müller-Wille R, Klebl F, Ott C, Strauch U, Piso P, Schlitt HJ, Agha A. Intraabdominal septic complications following bowel resection for Crohn’s disease: detrimental influence on long-term outcome. Int J Colorectal Dis. 2008;23:1167–1174.

21.  Tsujinaka S, Konishi F. Drain vs No Drain After Colorectal Surgery. Indian journal of surgical oncology. 2011;2(1):3-8.

22.  Hoffmann J, Shokouh-Amiri MH, Damm P, Jensen R. A prospective, controlled study of prophylactic drainage after colonic anastomoses. Dis Colon Rectum. 1987;30(6):449–452.

23.  Komen N, Bruin RW, Kleinrensink GJ, Jeekel J, Lange JF. Anastomotic leakage, the search for a reliable biomarker.A review of the literature. Colorectal Dis. 2008;10(2):109–115.

24.  Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de SE, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–196.

25.  Rogers JP, Dobradin A, Kar PM, Alam SE. Overnight Hospital Stay After Colon Surgery for Adenocarcinoma. JSLS: Journal of the Society of Laparoendo-scopic Surgeons. 2012;16 (2):333-336.

Corresponding Author

Dr Ninad Sawant

Resident, Department of Surgery,

Government Medical College, Nagpur India