Title: Sonographic Evaluation of Solitary Thyroid Nodule with Pathologic Correlation
Authors: Nandan Kumar L. D, Shilpa N
DOI: https://dx.doi.org/10.18535/jmscr/v4i10.65
Thyroid nodules are most common problems encountered in clinical practice. There should be proper diagnostic work up to select patients for surgical intervention, who have high chances of harbouring malignancy in the nodule. Ultrasound plays major role in differentiating benign and malignant nodule. Present study is undertaken to identify the various imaging features in thyroid nodules that are associated with benignity and malignancy. To know sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of ultrasonography as diagnostic module for solitary thyroid nodules. Materials and Methods: Present study included 60 patients with solitary thyroid nodule. Transverse and longitudinal real time ultrasound imaging of thyroid gland were performed. Ultrasound appearances of size, shape echogenicity, internal architecture, margins, halo, vascularity, presence or absence of lymph nodes were observed. On the basis of which nodule was classified in to benign or malignant /suspicious for malignancy. Pathological reports were considered standard for comparison. Diagnostic value of ultrasonography was calculated by sensitivity specificity, positive predictive value and negative predictive value. Result and discussion: 60 thyroid nodules were evaluated, with Male: Female ratio of1:5.6. Age of patients ranged from 18 to 63 years with mean age of 36+8.2 years. Sensitivity, specificity, PPV and NPV of ultrasonography as diagnostic tool are 70.0%, 98%, 87.5%, 96% respectively. These statistics correlate well with previous studies. Conclusion: Ultrasound is a sensitive and specific modality in assessment of thyroid nodules with good overall accuracy. Keywords- Solitary thyroid nodule, Colloid nodule, Papillary carcinoma, Follicular adenoma, Ultrasonography. 1. Ali A, Jasir M. Sonological and Pathological Evaluation of Solitary Nodule Thyroid. IOSR J Dental Med Sci 2013;16(3):1-8 2. Wiest PW, Hartshorne MF, Inskip PD, et al. Thyroid palpation versus high-resolution thyroid ultrasonography in the detection of nodules. J Ultrasound Med 1998;17: 487–496. 3. Carroll BA. Asymptomatic thyroid nod- ules: incidental sonographic detection. AJR Am J Roentgenol 1982;138:499–501. 4. Anuradha Kapali, Jaipal B R, Raghuram P, Ravindra Bangar, Sateesh Kumar Atmakuri. Role of ultrasonogra- phy in thyroid nodules with pathological correlation. Int J Contemporary Med Res 2016;3(5):1451-3. 5. Risk of malignancy in non-palpable thyroid nodule;predictive value of ultrasound and color Doppler features.J clin Endocrinol metab 2002;87(5):1941-1946. 6. Hoang JK, Lee WK, Lee M, Johnson D, Farrell S. US features of thyroid maligna-ncy: pearls and pitfalls. Radiographics 2007:27:847- 65. 7. Mallikarjunappa B, Ashish S R, Ultrasound Evaluation of Thyroid Nodules and its Pathological Correlation, JIMSA 2014;27 (1);8-11. 8. Seiberling KA, Dutra JC, Grant T et al: Role of intrathyroidal calcification detected on ultrasound as a marker of malignancy. Laryngoscope 2004; 114(10):1753-7. 9. Kimoto et al the efficiency of performing FNAC following mass gaining for thyroid tumors to avoid unnecessary surgery, surge today 1999;29(9) 880-3. 10. ChanBK, Desser TS, McDougall IR, Weigel RJ, Jeffrey RB Jr. Common and uncommon sonographic features of papillary thyroid carcinoma. J Ultrasound Med2003; 22(10): 1083–90. 11. TakiS, Terahata S, Yamashita R, et al. Thyroid calcifications: sonographic patterns and incidence of cancer. Clin Imaging2004; 28(5):368–371. 12. Sreeramulu P N,Venkatachalapathy T S, Prathima S, A Prospective Study Of Clinical, Sonological And Pathological Evaluation Of Thyroid Nodule. J Biosci Tech 2012; 3 (1):474- 78.Abstract
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