Abstract

Fine needle aspiration cytology is well accepted as a safe, reliable, minimal invasive and cost-effective method and can be applied for initial diagnosis of palpable lesions of skin. Its accuracy when applied by experienced and well trained practitioners matches that of histopathology in providing an equivocal diagnosis; so it can also be used as a very useful alternative to excision biopsy. A total of 57 patients with palpable nodular lesions were included in the study. All patients were randomly selected, irrespective of their age, religion, marital status, occupation or social status. Every patient underwent a FNAC done on OPD basis by a trained pathologist following a thorough clinical check-up. Every patient subjected to FNAC underwent skin biopsy, so subjected to histopathology. The results thus obtained from histopathology were matched with those of FNAC and a correlation was sought based on statistical tests. The overall diagnostic accuracy was 89.4%, the sensitivity was 94.4% and specificity was 100%.

Keywords:  FNAC, nodular lesions.

1.      Layfield LJ, Anders KH, Glasgow BJ, Mirra JM. Fine needle aspiration of primary soft tissue lesions. Arch. Pathol lab med 1986;110:420-4.

2.    Frable WJ. Fine-needle aspiration biopsy: A review. Hum Pathol 1983;14:9-28

3.    Leonforte JF, Palmoplantareepi-dermiszyste. Hautarzt 1978;29: 65742.Fisher BK, MacPhersonM. Epidermoid cyst of the sole. J AM Acad Dermatol1986;15:1127

4.    Onuigbo WIB.vulval epidermal cyst in the Igbos of Nigeria. Arch Dermatol 1976;112:1405

5.      Gonzalez S, Duarte I. Benign fibrous histiocytoma of the skin: a morphologic study of 290 cases. Pathol Res Pract 174:379-391, 1982.

6.      Meister P, Konrad E, Krauss F. Fibrous histiocytoma: a histological and statistical analysis of 155 cases. Pathl Res Pract 162:361-371, 1978.

7.      Brasfield RD, Das Gupta TK. Soft tissue tumors: benign tumors of adipose tissue. Cancer 19:3-8, 1969.

8.      Rao VK, Weiss SW. Angiomatosis of soft tissue: an analysis of the histologic features and clinical outcome in 51 cases. Am J Surg Pathol 16:764-771, 1992.

9.      Allen PW, Enzinger FM. Hemangiomas of skeletal muscle: an analysis of 89 cases. Cancer 29:8-22, 1972.

10.  Nichols GE, Gaffey MJ, Mills SE, Weiss LM. Lobular capillary hemangioma: an immunohistochemical study including steroid hormone receptor status. Am J Clin Pathol 97:77-85, 1992.

11.  Iwashita T, Enjoji M. Plexiforme neurilemmoma: a clinicopathologic and immunohistochemical anaysis of 23 tumors from 20 patients. Virchows Arch A Pathol Anat Histopathol 422:305-309, 1986.

12.  Elder et. al. , Levers Histopathology of Skin; 2005: 575